Protein Info for HER17_RS07235 in Pectobacterium carotovorum WPP14

Annotation: heme utilization cystosolic carrier protein HutX

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 166 transmembrane" amino acids 120 to 138 (19 residues), see Phobius details TIGR04108: putative heme utilization carrier protein HutX" amino acids 5 to 157 (153 residues), 213.1 bits, see alignment E=9.1e-68 PF06228: ChuX_HutX" amino acids 21 to 157 (137 residues), 122.9 bits, see alignment E=4.3e-40

Best Hits

Swiss-Prot: 34% identical to HUTX_VIBCH: Intracellular heme transport protein HutX (hutX) from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)

KEGG orthology group: K07227, hypothetical protein (inferred from 99% identity to pwa:Pecwa_1520)

Predicted SEED Role

"Putative heme iron utilization protein" in subsystem Iron acquisition in Vibrio

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (166 amino acids)

>HER17_RS07235 heme utilization cystosolic carrier protein HutX (Pectobacterium carotovorum WPP14)
MTMTLNELLATNPDGTLEEIAGKYNTSLFAVVEALPAAQRTLATGDRFDQVWDTIATWGE
VTLISHTADAILEFKSELPTGTHRHGYFNLRGKNGLSGHIRATSCQHIAFIERKFMGMDT
ASVVFFNASGAAMFKIFLGRDSHRQLLSAQVEAFRALASELQPEQV