Protein Info for HER17_RS06850 in Pectobacterium carotovorum WPP14

Annotation: formate/nitrite transporter family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 312 transmembrane" amino acids 63 to 84 (22 residues), see Phobius details amino acids 92 to 112 (21 residues), see Phobius details amino acids 141 to 165 (25 residues), see Phobius details amino acids 192 to 211 (20 residues), see Phobius details amino acids 218 to 245 (28 residues), see Phobius details amino acids 257 to 280 (24 residues), see Phobius details PF01226: Form_Nir_trans" amino acids 45 to 282 (238 residues), 174.4 bits, see alignment E=1.4e-55

Best Hits

Swiss-Prot: 66% identical to YFDC_ECOLI: Inner membrane protein YfdC (yfdC) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 92% identity to eca:ECA3084)

Predicted SEED Role

"putative transport"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (312 amino acids)

>HER17_RS06850 formate/nitrite transporter family protein (Pectobacterium carotovorum WPP14)
MNPPSESRQIRQEKERDVAVESEESTQGKAIDIDEDHLPSPAAAIHEEIRQEGQKELERD
AMALLWSAIAAGISMGTSFMAVGMLHTPLAGVPGGFLLECFGYTIGFVIVIMARQQLFTE
NTVTAVLPIMHKPTRSNFCLLGRLWFVVLAGNLIGTALAALAFTYMPVFDGETREALVDI
AMKVMKHSPTEMFANAVVSGWIIATMVWMLPRAYSAKLWIIIIMTWMIAFSNLTHIVAGA
SEIFYLVFIGHIPWQAFIWPFALPTLAGNIIGGTFIFALISHAQIRNDMSSSSHGKRQKV
QGNEEEEHRQKR