Protein Info for HER17_RS06520 in Pectobacterium carotovorum WPP14

Annotation: UDP-4-amino-4-deoxy-L-arabinose aminotransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 382 PF01041: DegT_DnrJ_EryC1" amino acids 11 to 373 (363 residues), 429.6 bits, see alignment E=1.7e-132 PF00155: Aminotran_1_2" amino acids 36 to 161 (126 residues), 37.1 bits, see alignment E=3.3e-13 PF05889: SepSecS" amino acids 38 to 164 (127 residues), 22.6 bits, see alignment E=6.4e-09

Best Hits

Swiss-Prot: 97% identical to ARNB_PECCP: UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase (arnB) from Pectobacterium carotovorum subsp. carotovorum (strain PC1)

KEGG orthology group: K07806, UDP-4-amino-4-deoxy-L-arabinose-oxoglutarate aminotransferase [EC: 2.6.1.87] (inferred from 97% identity to pct:PC1_2928)

MetaCyc: 72% identical to UDP-4-amino-4-deoxy-L-arabinose aminotransferase (Escherichia coli K-12 substr. MG1655)
RXN0-1863 [EC: 2.6.1.87, 2.6.1.92]

Predicted SEED Role

"Bacillosamine/Legionaminic acid biosynthesis aminotransferase PglE; 4-keto-6-deoxy-N-Acetyl-D-hexosaminyl-(Lipid carrier) aminotransferase"

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.6.1.87 or 2.6.1.92

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (382 amino acids)

>HER17_RS06520 UDP-4-amino-4-deoxy-L-arabinose aminotransferase (Pectobacterium carotovorum WPP14)
MTDFLPFSRPSMGEEEIAAVAEVLRSGWITTGPKCQQLEQAFCQRIGCRQAIAVSSATGG
MHVTLMALGIGPGDEVITPSQTWVSTVNIITLLGAEPVMVDVDRHTLMVRPQDIEAAITP
KTKAIIPVHYAGAPADLDALRALSERYGIPLIEDAAHAVGTQYRDEWIGARGTAIFSFHA
IKNITCAEGGMVVTDDEALAERLRSLKFHGLGVDAFDRQLQGRKPQAEVVTPGFKYNLAD
INAAIALVQLDKLPAINARRQQLAARYLTQLRSLPLQPLAVPDYPHLHAWHLFMVRVDEA
RCGISRDSLMAALQAHGIGTGLHFRAVHTQKYYRERYPHLRLPATEWNSASLMTLPLFPD
MQDSDVDRVVAALTSILESVRD