Protein Info for HER17_RS06355 in Pectobacterium carotovorum WPP14

Annotation: sugar ABC transporter permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 282 transmembrane" amino acids 12 to 34 (23 residues), see Phobius details amino acids 81 to 100 (20 residues), see Phobius details amino acids 112 to 136 (25 residues), see Phobius details amino acids 143 to 162 (20 residues), see Phobius details amino acids 187 to 209 (23 residues), see Phobius details amino acids 246 to 267 (22 residues), see Phobius details PF00528: BPD_transp_1" amino acids 101 to 274 (174 residues), 67.8 bits, see alignment E=5.5e-23

Best Hits

Swiss-Prot: 66% identical to GANQ_BACSU: Putative arabinogalactan oligomer transport system permease protein GanQ (ganQ) from Bacillus subtilis (strain 168)

KEGG orthology group: K10110, maltose/maltodextrin transport system permease protein (inferred from 99% identity to pct:PC1_2960)

Predicted SEED Role

"Maltose/maltodextrin ABC transporter, permease protein MalG" in subsystem Maltose and Maltodextrin Utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (282 amino acids)

>HER17_RS06355 sugar ABC transporter permease (Pectobacterium carotovorum WPP14)
MKKHSVKRQNFIKLGLTYLLLTIVAIIIIYPLIWTVGASLNPGNSLLNTSIIPDNFSFIH
YEELFNGQIDYAAWYWNSMKISFLTMILTLVSVSFTAYSFSRFRFRGRQNGLMLFLLLQM
IPQFSALIAIFVLAQMLGLVNSHIALVLVYVGGMIPMNTYLMKGYLDAIPKDLDESARMD
GAGNFRIFIEIIMPLSKPIIAVIALFSFTGPLGDFILSSTILRTPDQYTLPIGLYNLVSQ
KMGASYTTYAAGAVLIAVPVAILYLSLQKYFVSGLTSGGTKG