Protein Info for HER17_RS05865 in Pectobacterium carotovorum WPP14

Annotation: TolC family outer membrane protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details TIGR01844: type I secretion outer membrane protein, TolC family" amino acids 21 to 424 (404 residues), 313.2 bits, see alignment E=1.5e-97 PF02321: OEP" amino acids 26 to 216 (191 residues), 92.8 bits, see alignment E=1.2e-30 amino acids 236 to 405 (170 residues), 100.4 bits, see alignment E=5.8e-33

Best Hits

KEGG orthology group: K12543, outer membrane protein LapE (inferred from 96% identity to pct:PC1_3061)

Predicted SEED Role

"Agglutination protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (450 amino acids)

>HER17_RS05865 TolC family outer membrane protein (Pectobacterium carotovorum WPP14)
MMRRHSFALLPFITLFSTATHAETIQEAIKSTLYTHPEVSAAINSRFSAEHDLRAAKGGY
LPSITLSAGVGREETDSPSTRASTNKRVELSRQESSINLSQTVFDGFATSSEVGRQRATV
NSRAYKVLNTSEATALDTVQVYLSVLQRQEFVRLAEANLASHERIYDQIRLRSEQGVGRL
ADLDQAEARLAQARNNVLTEKTNLDDAKTNYMSIVGKVPENLVMPDASVIKLPASLEEAL
RIMLANSPALKSAESDIEATQQQYETSKSTFYPRLNVELSRTMDSNVDGTRGQNNEWQAM
LRMRYNLYEGGSSKANMESKAYQVKEAQDVRNNALRLLSEELKLAWSALNNSRQQLPIAA
EYADRSMKVRTAYQKQFGLGERTLLDLLDSENELFTAQRRLVEVRFTSLYTEYRIASRMG
ELLNRLAIPAPDAGTSLTNVTPQAELPSLN