Protein Info for HER17_RS05675 in Pectobacterium carotovorum WPP14

Annotation: sulfate ABC transporter permease subunit CysT

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 270 transmembrane" amino acids 12 to 38 (27 residues), see Phobius details amino acids 61 to 85 (25 residues), see Phobius details amino acids 97 to 120 (24 residues), see Phobius details amino acids 132 to 152 (21 residues), see Phobius details amino acids 184 to 202 (19 residues), see Phobius details amino acids 241 to 262 (22 residues), see Phobius details TIGR00969: sulfate ABC transporter, permease protein" amino acids 5 to 265 (261 residues), 299.5 bits, see alignment E=2.4e-93 TIGR02139: sulfate ABC transporter, permease protein CysT" amino acids 8 to 267 (260 residues), 399.3 bits, see alignment E=8.7e-124 PF00528: BPD_transp_1" amino acids 75 to 269 (195 residues), 76.6 bits, see alignment E=1e-25

Best Hits

Swiss-Prot: 47% identical to CYST_SALTY: Sulfate transport system permease protein CysT (cysU) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

KEGG orthology group: K02046, sulfate transport system permease protein (inferred from 98% identity to eca:ECA3298)

MetaCyc: 46% identical to sulfate/thiosulfate ABC transporter inner membrane subunit CysU (Escherichia coli K-12 substr. MG1655)
ABC-19-RXN [EC: 7.3.2.5]; ABC-7-RXN [EC: 7.3.2.5, 7.3.2.3]; 7.3.2.3 [EC: 7.3.2.5, 7.3.2.3]; TRANS-RXN0-478 [EC: 7.3.2.5, 7.3.2.3]; TRANS-RXN0-479 [EC: 7.3.2.5, 7.3.2.3]

Predicted SEED Role

"Sulfate transport system permease protein CysT" in subsystem Cysteine Biosynthesis

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.3.2.3 or 7.3.2.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (270 amino acids)

>HER17_RS05675 sulfate ABC transporter permease subunit CysT (Pectobacterium carotovorum WPP14)
MSQRSSSVIPGFGLTLGFSLSYLGLIVLIPLAGMFLYASQLTFGQFWDLITSRQVLFSLR
LSFGTALAAAFINGILGTLLAWVLVRYTFPGRKVIDAMIDMPFALPTAVAGIALTALYAP
NGLIGSLFPFKIAYTGIGITLALIFVTLPFVVRTLQPVLADIPKEVEEAAACLGARPLQV
FRHVLLPALLPAWLTGFALAFARGVGEYGSVVFIAGNIPFKTEILPLLIVSKLDQYDYKG
ATGIGVFMLLVSFIMLLLINVLQRRIQPKL