Protein Info for HER17_RS04315 in Pectobacterium carotovorum WPP14

Annotation: basic amino acid ABC transporter substrate-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 256 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details PF00497: SBP_bac_3" amino acids 28 to 247 (220 residues), 208.5 bits, see alignment E=9.2e-66 PF10613: Lig_chan-Glu_bd" amino acids 42 to 119 (78 residues), 40.4 bits, see alignment E=2.9e-14

Best Hits

Swiss-Prot: 42% identical to HISJ_NEIGO: Probable histidine-binding protein (hisJ) from Neisseria gonorrhoeae

KEGG orthology group: None (inferred from 98% identity to pwa:Pecwa_3512)

Predicted SEED Role

"Glutamine ABC transporter, periplasmic glutamine-binding protein (TC 3.A.1.3.2)" (TC 3.A.1.3.2)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (256 amino acids)

>HER17_RS04315 basic amino acid ABC transporter substrate-binding protein (Pectobacterium carotovorum WPP14)
MFKKLLFVGALFATALSTSAFAAEPTYVVGSGGTYRPFEFENAQKELEGFDIDIIKAIAK
AENFNIKLINTPWEGIFATLNSGDRDIIISGITITDKRKQMVDFSAPYFPAEQSIVVPKG
STIDSIAALKDHKVGVVNSSTADIVVSDVLGKNSTSIKRFDNTPLMLQELYEDGVGAAVG
DVGVVKFYIKTHPEKQFNLVSDAKFERQYFGIAVAKGNDQLRAKINSGLKKIVADGTYAK
IYQTWFDNNVPTLPAE