Protein Info for HER17_RS04065 in Pectobacterium carotovorum WPP14

Annotation: PAS domain-containing methyl-accepting chemotaxis protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 511 transmembrane" amino acids 167 to 185 (19 residues), see Phobius details amino acids 191 to 208 (18 residues), see Phobius details PF13426: PAS_9" amino acids 19 to 106 (88 residues), 34.7 bits, see alignment E=4.7e-12 TIGR00229: PAS domain S-box protein" amino acids 21 to 116 (96 residues), 40.9 bits, see alignment E=1.1e-14 PF00989: PAS" amino acids 24 to 110 (87 residues), 36.2 bits, see alignment E=1.4e-12 PF08447: PAS_3" amino acids 31 to 111 (81 residues), 47.2 bits, see alignment E=5.5e-16 PF00672: HAMP" amino acids 208 to 258 (51 residues), 28.4 bits, see alignment 4.3e-10 PF00015: MCPsignal" amino acids 322 to 478 (157 residues), 165.9 bits, see alignment E=2e-52

Best Hits

Swiss-Prot: 44% identical to AER_ECOLI: Aerotaxis receptor (aer) from Escherichia coli (strain K12)

KEGG orthology group: K03776, aerotaxis receptor (inferred from 96% identity to pct:PC1_3399)

Predicted SEED Role

"Aerotaxis sensor receptor protein" in subsystem Bacterial Chemotaxis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (511 amino acids)

>HER17_RS04065 PAS domain-containing methyl-accepting chemotaxis protein (Pectobacterium carotovorum WPP14)
MRLNTPVTQQEYLLDMDTILMSTTNIHSHITYANSAFITVSGFSEEQLINQPHNIVRHPD
MPVEAYADMWFTLKQGDSWTGLVKNRRNNGDHYWVRANVTPVYQQEQLAGYISVRNTPSA
EEIKYAETLYSAVQKKQAGSRKFYKGLVVRTGLFSPLSLLQKLPVRWRLRLAVLAVGLIP
ALLAFSGMNPLWLLALTLLLIVIMDQFLQKQIAQPIRMILKQAQHVVSGRKVKHVHLNRV
DEIGLLLRSVNQFALNLHSLVDDVSTQVNGITNVSHKLAENNVDLNTRTEETSANLQQTA
AAIEEITVAVQQSAETAAQATTMAEAASNTAFKGGNIMKETIGMMDSISSASDKIVDIIG
VIDSIAFQTNILALNAAVEAARAGVQGRGFAVVAAEVRNLAQHSASAAKEIKTLIDANVE
SVKQGSTMVENAGKHISDIVDEVLQVSTMIKEISNATHEQTSALGLINTSIAQIEQMTQR
NTDMVTHSTEAAEGLNLQARRLNSAINVYGS