Protein Info for HER17_RS03310 in Pectobacterium carotovorum WPP14

Annotation: serine hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 398 PF00144: Beta-lactamase" amino acids 22 to 381 (360 residues), 227.5 bits, see alignment E=1.3e-71

Best Hits

Swiss-Prot: 51% identical to ESTB_BURGA: Esterase EstB (estB) from Burkholderia gladioli

KEGG orthology group: None (inferred from 86% identity to pct:PC1_3564)

Predicted SEED Role

"Beta-lactamase class C and other penicillin binding proteins" in subsystem Beta-lactamase

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (398 amino acids)

>HER17_RS03310 serine hydrolase (Pectobacterium carotovorum WPP14)
MITPVFPLDTRAATAPLSARIQATVQQALDDGRLVGAVVLVARNGELLHQQAAGWSDRES
ARPMALDAIFRLASVSKPIVSVTALVLVAQGRLNLDEDITLWMPTFQLRLADGRPANVTA
RQLLSHTAGLGYRFFESHADGPYAQAGVSDGMDASGISLTENLRRIASVPLQYVPGEAWG
YSLATDVLGALIERIHGMSLSEAVRQLVTDPLGMHDTGFVVRDPSRLTTAYVNDTPQPHR
LTEGETVSPFDGAIGIAYSPSRIFDPQAFPSGGAGMAGTAWDLLRLLEALRKAGGLLPLP
DALIEEMGRDQTQGLDLPNAPGCGFGLGFSVLRDPQLAESPESSGTWRWGGAYGHSWFVD
RTQGLSVVAFTNTMYEGMSGSFVTELRDAVYGELEAAR