Protein Info for HER17_RS02405 in Pectobacterium carotovorum WPP14
Annotation: archaetidylserine decarboxylase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 94% identical to PSD_PECAS: Phosphatidylserine decarboxylase proenzyme (psd) from Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672)
KEGG orthology group: K01613, phosphatidylserine decarboxylase [EC: 4.1.1.65] (inferred from 94% identity to eca:ECA3966)MetaCyc: 73% identical to phosphatidylserine decarboxylase proenzyme (Escherichia coli K-12 substr. MG1655)
Predicted SEED Role
"Phosphatidylserine decarboxylase (EC 4.1.1.65)" in subsystem Glycerolipid and Glycerophospholipid Metabolism in Bacteria (EC 4.1.1.65)
MetaCyc Pathways
- superpathway of phospholipid biosynthesis III (E. coli) (11/12 steps found)
- superpathway of cardiolipin biosynthesis (bacteria) (10/13 steps found)
- phosphatidylserine and phosphatidylethanolamine biosynthesis I (2/2 steps found)
- cardiolipin and phosphatidylethanolamine biosynthesis (Xanthomonas) (3/4 steps found)
- superpathway of phospholipid biosynthesis II (plants) (10/28 steps found)
KEGG Metabolic Maps
Isozymes
No predicted isozymesUse Curated BLAST to search for 4.1.1.65
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (342 amino acids)
>HER17_RS02405 archaetidylserine decarboxylase (Pectobacterium carotovorum WPP14) MLDNIKIKLQYWLPKIWLTRLAGWGANKRAGKLTKLVIDLFVRQYNVNMQEAQQPDTASY RTFNEFFVRPLRPGIRPVDPHAHRLVQPADGVLSQFGPITDGKLIQAKNHDYTLEALLAG NYVMADLFRDGLFATIYLSPRDYHRLHMPCDGVLREMIYVPGDLFSVNLLTADNVPNLFA RNERVICLFDTEFGPVAQILVGATIVGSIETVWSGVVTPPREGIIKRWTYPQAGEEGAVV LAKGEEMGRFKLGSTVINLFATGNNLQFAAHLNTMSVTRMGEPFAEVCQDEQAPVVFPEG TELEENDTAPSPVAATSEPVKVEGQHPAADAAGQTGHKPDAP