Protein Info for HER17_RS02235 in Pectobacterium carotovorum WPP14

Annotation: DUF494 family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 157 PF04361: DUF494" amino acids 1 to 155 (155 residues), 199.3 bits, see alignment E=1.6e-63

Best Hits

Swiss-Prot: 98% identical to SMG_PECAS: Protein Smg (smg) from Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672)

KEGG orthology group: K03747, Smg protein (inferred from 98% identity to pct:PC1_3787)

Predicted SEED Role

"Protein of unknown function Smg" in subsystem Conserved gene cluster associated with Met-tRNA formyltransferase

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (157 amino acids)

>HER17_RS02235 DUF494 family protein (Pectobacterium carotovorum WPP14)
MFDVLMYLFESYIHNETEMRVDQDTLTDDLTRAGFHRNDIYSALSWLEKLADIQEGQTAP
LYLANDPLAMRIYTQDEALRLDAECRGFLLFLEQIQVLNLETREMIIERVMALETQEFDL
EDLKWVILMVLFNVPGCENAYQQMEELLFEVNDGYVQ