Protein Info for HER17_RS02010 in Pectobacterium carotovorum WPP14

Annotation: transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 240 PF08348: PAS_6" amino acids 29 to 137 (109 residues), 127.5 bits, see alignment E=2.3e-41 PF13309: HTH_22" amino acids 172 to 228 (57 residues), 68.6 bits, see alignment E=3.7e-23

Best Hits

Swiss-Prot: 86% identical to YHEO_SHIFL: Uncharacterized protein YheO (yheO) from Shigella flexneri

KEGG orthology group: None (inferred from 100% identity to pwa:Pecwa_4014)

Predicted SEED Role

"YheO-like PAS domain"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (240 amino acids)

>HER17_RS02010 transcriptional regulator (Pectobacterium carotovorum WPP14)
MSNSLVSGESYELDLLDERPFSQTDYEILKSYEAVVDGLAMLIGEHCEIVLHSLEDLKCS
AVRIANGEHTGRKIGSPITDLALRMLHDMAGEDSSVSKAYFTRAKSGVLMKSVTIAIRNR
DQRVIGLLCINMNLDVPFSQIVQTFIPPETHDAASSVNFASSVDDLVAQTLEFSIEEVNA
DRNVSNNAKNRQIVLSLYEKGIFDIKDAINQVAERLNISKHTVYLYIRQFKSGDFSGHER