Protein Info for HER17_RS01200 in Pectobacterium carotovorum WPP14

Annotation: amino acid permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 463 transmembrane" amino acids 21 to 40 (20 residues), see Phobius details amino acids 46 to 62 (17 residues), see Phobius details amino acids 95 to 121 (27 residues), see Phobius details amino acids 127 to 148 (22 residues), see Phobius details amino acids 156 to 179 (24 residues), see Phobius details amino acids 200 to 221 (22 residues), see Phobius details amino acids 242 to 263 (22 residues), see Phobius details amino acids 277 to 301 (25 residues), see Phobius details amino acids 330 to 355 (26 residues), see Phobius details amino acids 361 to 382 (22 residues), see Phobius details amino acids 403 to 425 (23 residues), see Phobius details amino acids 431 to 452 (22 residues), see Phobius details PF00324: AA_permease" amino acids 18 to 430 (413 residues), 364.2 bits, see alignment E=1e-112 PF13520: AA_permease_2" amino acids 22 to 430 (409 residues), 132.7 bits, see alignment E=1.8e-42

Best Hits

Swiss-Prot: 80% identical to YIFK_SALTY: Probable transport protein YifK (yifK) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

KEGG orthology group: K03293, amino acid transporter, AAT family (inferred from 98% identity to pct:PC1_3999)

MetaCyc: 81% identical to threonine/serine:H+ symporter ThrP (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-71; TRANS-RXN-72

Predicted SEED Role

"Probable transport protein YifK"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (463 amino acids)

>HER17_RS01200 amino acid permease (Pectobacterium carotovorum WPP14)
MAEDVKQEKLHRGLEARHIELIALGGTIGVGLFMGAASALKWAGPSVLLAYIVAGIFVFF
IMRSMGEMLYLEPVAGSFAVYAHKYMNPFFGYLTAWGYWFMWMAVGISEITAIGVYVQYW
FPDLPQWIPAIAAVALVAGANLAAVRLYGEIEFWFAMIKITTIVVMIVVGVGIIFFGFGN
HGQATGFSNLTEHGGFLAGGWKGLLFALCLVVASYQGVELVGITAGEAKNPQVTLKRAIN
NILWRILIFYVGAIFVIVTIFPWNEIGTSGSPFVMTFAKIGITAAAGIINFVVLTAALSG
CNSGMYSCGRMLYSLANNRQLPAWLGKVTASGVPAAGVMISILCLMAGSVLNYIIPNPEK
VFVYVYSASVLPGMVPWFVVLISQLRFREQHRAALVAHPFKSVLFPWVNYLTMAFLLCVL
VGMYINIDTRMSLLVGVAFLAVVSLCYFALGLGKKMSLTEDKS