Protein Info for HER17_RS00365 in Pectobacterium carotovorum WPP14

Annotation: UDP-forming cellulose synthase catalytic subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 899 signal peptide" amino acids 1 to 16 (16 residues), see Phobius details transmembrane" amino acids 31 to 50 (20 residues), see Phobius details amino acids 150 to 167 (18 residues), see Phobius details amino acids 173 to 190 (18 residues), see Phobius details amino acids 198 to 216 (19 residues), see Phobius details amino acids 228 to 252 (25 residues), see Phobius details amino acids 523 to 542 (20 residues), see Phobius details amino acids 545 to 569 (25 residues), see Phobius details amino acids 639 to 659 (21 residues), see Phobius details amino acids 665 to 690 (26 residues), see Phobius details amino acids 833 to 855 (23 residues), see Phobius details TIGR03030: cellulose synthase catalytic subunit (UDP-forming)" amino acids 146 to 828 (683 residues), 954.7 bits, see alignment E=1.3e-291 PF13641: Glyco_tranf_2_3" amino acids 275 to 500 (226 residues), 61.7 bits, see alignment E=2.8e-20 PF00535: Glycos_transf_2" amino acids 278 to 447 (170 residues), 83 bits, see alignment E=7.2e-27 PF13506: Glyco_transf_21" amino acids 338 to 499 (162 residues), 30.2 bits, see alignment E=9.4e-11 PF13632: Glyco_trans_2_3" amino acids 356 to 566 (211 residues), 72.9 bits, see alignment E=1e-23 PF03552: Cellulose_synt" amino acids 446 to 569 (124 residues), 44.6 bits, see alignment E=2.5e-15 PF07238: PilZ" amino acids 694 to 790 (97 residues), 43.6 bits, see alignment E=9.5e-15

Best Hits

KEGG orthology group: K00694, cellulose synthase (UDP-forming) [EC: 2.4.1.12] (inferred from 73% identity to ctu:CTU_40340)

Predicted SEED Role

"Cellulose synthase catalytic subunit [UDP-forming] (EC 2.4.1.12)" (EC 2.4.1.12)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.4.1.12

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (899 amino acids)

>HER17_RS00365 UDP-forming cellulose synthase catalytic subunit (Pectobacterium carotovorum WPP14)
MSGILHLFLVPPARQAIQQRYHGYRQQGASAFAAFLATLFAILGWIFLRLESEGWQQIRA
QRTYWFPHISPQRPRPADILRYLTQGIWLLTIKNGQLPTSRRNYFSALPRWRQRYMNAQQ
ALFARFSHANTDDREDHESGSAKTSRIQRLVTVILSLLCAALALLCITQPFDLLSQFIFM
ALLWGIAMLVRNMPGRMPTLMMIALSFTVSCRYLWWRYTETLNWDDPLSLICGLLLLAAE
TYAWVVLVLGYFQTIWPLNRHPVSLPEDSKTWPTVDLMIPTYNEPLSVVKPTVYAALGID
WPKDKLNIYILDDGGRAEFKTFAEKVGVHYIARVTHEHAKAGNINNALKQAEGEFVAIFD
CDHVPTRSFLQLTMGWFFKDKKLAMLQTPHHFFSPDPFERNLGRFRRTPNEGTLFYGLVQ
DGNDMWDATFFCGSCAILRRKPLDEIGGIAVETVTEDAHTSLRLHRRGYSSAYIRIPQAA
GLATESLSAHIGQRIRWARGMVQIFRLDNPLFGKGLKLGQRLCYANAMMHFLSGIPRLIF
LTAPLAFLLLHAYIIFAPALAIALYVLPHMVHASLTNSRIQGRYRHSFWSEIYETVLAWY
IARPTTVALFNPHKGKFNVTAKGGLVEEQHVDWVITRPYLVLVLLNIAGVVYAGWRLIYG
PPEEIMTVLISLLWVMYNMTILGGAVAVAVEAKQVRQAHRVEMSMSAAILRADGHLFPCV
LRDYSDGGVGVEARESGILQVGDSVSLLLKRGQQEYAFPFSVTRAFDNKIGLRMTNLAIR
QHIDFIQCTFARADTWALWQDSFPQDKPVESLVDVLALGFRGYLRLADYAPPVIRNIILA
FLNTVVWVVSFIPRYVGKRPVTDSPGAALPEKNVHQGQTPSAHETRFAQENLFTAKTVA