Protein Info for HER17_RS00350 in Pectobacterium carotovorum WPP14

Annotation: cellulose biosynthesis protein BcsC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1189 PF13432: TPR_16" amino acids 390 to 452 (63 residues), 17.6 bits, see alignment 1.6e-06 amino acids 642 to 694 (53 residues), 20.2 bits, see alignment (E = 2.5e-07) PF14559: TPR_19" amino acids 507 to 560 (54 residues), 30.8 bits, see alignment 1.1e-10 amino acids 647 to 706 (60 residues), 38.9 bits, see alignment 3.1e-13 PF05420: BCSC_C" amino acids 836 to 1167 (332 residues), 405.7 bits, see alignment E=5.8e-125

Best Hits

Swiss-Prot: 51% identical to BCSC_ECOLI: Cellulose synthase operon protein C (bcsC) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 90% identity to eca:ECA4374)

Predicted SEED Role

"Cellulose synthase operon protein C"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1189 amino acids)

>HER17_RS00350 cellulose biosynthesis protein BcsC (Pectobacterium carotovorum WPP14)
MSRLHSGRWEGLIQNTQDWTTIAKGDNALKANNLALNWLRLLPLLLVTAPQAYSAETASP
EQFLMEQVRLGEASNKDDLVRQSLYRLELINPDNPEVIAAKLRLVLRQGDQAQARQQLER
LKAVAPDSALYRQAETTLALTQEAARQQLQQARLLSTAGRYAEAKAQYDTLFHGEPPTLD
LAVEYWRLVSRLPNQEPVAIKQLEALDQVYPDNVPLRMVLSRLLFSQDRNEQAYPLLQQL
SNDPVGRSQAASLWLEIIGRMPVTSQSVAELNRFLTVFKDGEQAETARKELNRQQGMMTD
PTYQARLRGLAQVESGGGNSATLNELNKALTATPNDPELIGAVGLVYLRAGDRAKALTQF
QKALQADTDRLNSGKWEGLIQSTQYWNTIAEGDNALKANNLPLARQKYQQARQMDNTNAY
ALIGLGDVAVASKNDAAAQPLYQQALHLEPGNDNALRGLVGIYQRQSPEKALAYLNSLSP
SQQNAMREPLAALRLDILKQQADRLSEQQQWAQAEEKYRQANQQDPNDVWLAYRYAQTLR
QLGKTQQADSVVQRATSIPPTSAEKNYVYSLYLSSTNRDEQALAHLNTLPAAQWSDDMRD
LSQRLTMQTTLAKAEAIRDADDESAAIAFLRQQPADTRIDLLLADWALARGEYATALADY
QRIRTREPQNPDAQLGEIDAFIAQGQQDDARQRLNQLPMQAADTFNAQRRVANAWQAVGD
PQKSTALFRQLKIDAQKEPVGQTKALVYRDAARVEQQQSQPEQAQQDYKQAMVASGITPA
LPQSDDDYTRLTRNQAGDDWLQRGIRADAADLYRKQDITVTLDHDYGSSSGTGGVSDLSA
HDTMLQIEMPLYDGRAFFRTDTVQMNAGSFSADSNGAYRETFGTCATQDCFDGKSQKATG
TSVAAGWKNDRWSADIGTTPLGFDVVDVVGGASYSGDWRQIGWTATASRRPISSSLLAFG
GTKDPGTGITWGGVRATGVSLGLSYDRGEAHGVWSDFSVHQITGKNVADNDRARAMAGYY
YKLINEDNRRVTVGLNSMWWRYQKDLSGYSLGQGGYYSPQQYFSLGVPVNYRQRTENWSW
ELGGSLSWSRSSTKDQRRYPLVGLLGNAAITDRDAIEEGSSSSGFGYTARAIVERRLSSH
WTLGVGIDIQQAKNYTPSHGLIYLRYSASGWQGDLDSPPQPLTPYADFK