Protein Info for HER17_RS00090 in Pectobacterium carotovorum WPP14

Annotation: ABC transporter substrate-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 516 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details PF00496: SBP_bac_5" amino acids 66 to 430 (365 residues), 330.1 bits, see alignment E=9.8e-103

Best Hits

KEGG orthology group: K02035, peptide/nickel transport system substrate-binding protein (inferred from 99% identity to pct:PC1_0015)

Predicted SEED Role

"Dipeptide-binding ABC transporter, periplasmic substrate-binding component (TC 3.A.1.5.2)" in subsystem ABC transporter dipeptide (TC 3.A.1.5.2) or Bacterial Chemotaxis (TC 3.A.1.5.2)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (516 amino acids)

>HER17_RS00090 ABC transporter substrate-binding protein (Pectobacterium carotovorum WPP14)
MKKSTLALLFTVLFSSSPLVYSADLNIGLASSTTSMDPQFYVSGANSAMARNIFDGLVVQ
DEKQQIAPALATSWKVIDDKTWEFVLRPGVKFHDGSDFTAKDVIASIKRVALASKNSPSS
YAPYVSDIAEVIEVNPLTVRIKTKEASPLLLNNLSRISILPARLENVPTETLNSGKDVIG
TGPFKFVSWVPDDRVVLSRNDDYWGGKAEWDNVTVRVFKNSSARVAAVLSGDVDMIENVP
TADSSNIEKNQQLKTISTPGNRVIYLHMDQQREESPFAKGPDGKNPLLKKEVRQAMSLAI
NRQAIVDRVMEGQAVVASQLVPKGYPGYSASIPAPVYNPEKAKQELAAAGYPDGFTLTFH
ASNDRYPNDSKIAQAIGQMFTRAGIKTEVVTMPGSVYFSRASRLEFSLIMGGAAIETGEA
SGVLGPLLETFGPNAGQGNRGRYSNPVFDKTLNEARATLDETKRDALLAEAMNIGMNDLG
VIPVMFLSNTWAMKKQYTYVGRSDAYTLPYFVRSAK