Protein Info for HEPCGN_27335 in Escherichia coli ECOR38

Annotation: DUF2318 domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 459 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details transmembrane" amino acids 34 to 53 (20 residues), see Phobius details amino acids 60 to 80 (21 residues), see Phobius details amino acids 120 to 144 (25 residues), see Phobius details amino acids 152 to 177 (26 residues), see Phobius details amino acids 199 to 220 (22 residues), see Phobius details amino acids 245 to 266 (22 residues), see Phobius details PF10080: FtrD-like" amino acids 297 to 400 (104 residues), 97.2 bits, see alignment E=5.6e-32 PF04945: YHS" amino acids 408 to 454 (47 residues), 60.1 bits, see alignment 1.6e-20

Best Hits

KEGG orthology group: None (inferred from 100% identity to cko:CKO_02055)

Predicted SEED Role

"Fe2+ ABC transporter, substrate binding protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (459 amino acids)

>HEPCGN_27335 DUF2318 domain-containing protein (Escherichia coli ECOR38)
MSYFFVTTLQVFFCIALLSGVLWSRNDPPSLRPLTWTLLTGLIAGVLAGLFIHGSQPVQL
LLVGAEVMVSLLFVLSFWWASTRIRYLWQGILIFGAARHWALDPNLGGLTSTHVLNTDLL
LNLTAVVLAFAILCLAGVLCAMLLRRIRGLYWPLTLILLVMIWLPLSGNLLLLLMKLQVV
PLGKSLLSFVAKVTNNTALYNWAGAALLLALALCWLPALLRAFRQTRETEEPIAHRLALA
QRRNALRLWLVTIGCAVVVIAGQLWWDKVASQPPQLSEAVPVTLGSDGMVRLPVEQLRDG
KLHRFVWVADDGKAVRFFVINRYPDKLRFGVVFDACLLCGDQGYVMEGNQVICVACGVHI
FIPSIGKAGGCNPVPIENWHNDEKELVIPGKELATGVNYFSTVMTIKVTDPVDGSTLTNT
SADYKYSYGGKTWFFSSEANYERFRETPEQFVPADMREE