Protein Info for HEPCGN_26290 in Escherichia coli ECOR38

Name: yncD
Annotation: putative TonB-dependent receptor YncD

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 744 transmembrane" amino acids 17 to 67 (51 residues), see Phobius details PF07715: Plug" amino acids 85 to 195 (111 residues), 79.1 bits, see alignment E=5.1e-26 TIGR01783: TonB-dependent siderophore receptor" amino acids 86 to 739 (654 residues), 223.6 bits, see alignment E=2.7e-70 PF00593: TonB_dep_Rec" amino acids 281 to 706 (426 residues), 190.4 bits, see alignment E=1.6e-59 PF14905: OMP_b-brl_3" amino acids 395 to 633 (239 residues), 35.4 bits, see alignment E=1e-12

Best Hits

Swiss-Prot: 98% identical to YNCD_ECOLI: Probable TonB-dependent receptor YncD (yncD) from Escherichia coli (strain K12)

KEGG orthology group: K02014, iron complex outermembrane recepter protein (inferred from 98% identity to eco:b1451)

MetaCyc: 98% identical to pyrroloquinoline quinone outer membrane transporter (Escherichia coli K-12 substr. MG1655)
TRANS-RXN0-629

Predicted SEED Role

"Probable tonB-dependent receptor yncD precursor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (744 amino acids)

>HEPCGN_26290 putative TonB-dependent receptor YncD (Escherichia coli ECOR38)
MWSISCRYDYNFLNYLTYRAVSFSINLQFYYYDGVFPILNLAFFMKIFSVRQTVLPALLV
LSPVVFAADEQTMIVSAAPQVVSELDTPAAVSVVDGEEMRLATPRINLSESLTGVPGLQV
QNRQNYAQDLQLSIRGFGSRSTYGIRGIRLYVDGIPATMPDGQGQTSNIDLSSVQNVEVL
RGPFSALYGNASGGVMNVITQTGQQPPTIEASSYYGSFGSWRYGLKATGATGDGTQPGDV
DYTVSTTRFTTHGYRDHSGAQKNLANAKLGVRIDEASKLSLIFNSVDIKADDPGGLTKAE
WKANPQQAPRAEQYDTRKTIKQTQAGLRYERSLSAQDDMSVMMYAGERETTQYQSIPMAP
QLNPSHAGGVITLQRHYQGIDSRWTHRGELGVPLTFTTGLNYENMSENRKGYNNFRLNSG
VPEYGQKGELRRDERNLMWNVDPYLQTQWQLSEKLSLDAGVRYSSVWFDSNDHYVTPGNG
DDSGDASYHKWLPAGSLKYAMTDAWNIYLAAGRGFETPTINELSYRADGQSGMNFGLKPS
TNDTIEIGSKTRIGDGLLSLALFQTDTDDEIVVDSSSGGRTTYKNAGKTRRQGAELAWDQ
RFAGDFRVKASWTWLDATYRSNVCNEQDCNGNRMPGIARNMGFASIGYVPEDGWYAGTEA
RYMGDIMADDENTAKAPTYTLVGLFTGYKYNYHNLTVDLFGRVDNLFDKEYVGSVIVNES
NGRYYEPAPGRNYGIGVNVAWRFE