Protein Info for HEPCGN_25160 in Escherichia coli ECOR38

Name: ompW
Annotation: outer membrane protein OmpW

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 212 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details PF13505: OMP_b-brl" amino acids 7 to 212 (206 residues), 41.7 bits, see alignment E=1.4e-14 PF03922: OmpW" amino acids 23 to 212 (190 residues), 261.6 bits, see alignment E=5.1e-82

Best Hits

Swiss-Prot: 96% identical to OMPW_ECOLI: Outer membrane protein W (ompW) from Escherichia coli (strain K12)

KEGG orthology group: K07275, outer membrane protein (inferred from 98% identity to ssn:SSON_1910)

Predicted SEED Role

"Outer membrane protein W precursor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (212 amino acids)

>HEPCGN_25160 outer membrane protein OmpW (Escherichia coli ECOR38)
MKKLTVAALAVATLLSGSAFAHESGEFFMRAGSATVRPTEGAGGTLGSLGGFSVTNNTQL
GLTFTYMATDNIGVELLAATPFRHKIGTRATGDIATVHHLPPTLMAQWYFGDASSKFRPY
VGAGINYTTFFDNGFNDHGKEAGLSDLSLKDSWGAAGQVGVDYLINRDWLVNMSVWYMDI
DTTAKYKSGVTTVKDSVRLDPWVFMFSAGYRF