Protein Info for HEPCGN_24580 in Escherichia coli ECOR38

Annotation: host-nuclease inhibitor protein Gam

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 176 PF07352: Phage_Mu_Gam" amino acids 23 to 169 (147 residues), 137.5 bits, see alignment E=1.7e-44

Best Hits

Swiss-Prot: 62% identical to GAM_BPMU: Putative DNA ends protecting protein gam (gam) from Escherichia phage Mu

KEGG orthology group: None (inferred from 99% identity to stt:t1387)

Predicted SEED Role

"putative host-nuclease inhibitor protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (176 amino acids)

>HEPCGN_24580 host-nuclease inhibitor protein Gam (Escherichia coli ECOR38)
MAKSTKGAKRIKAAAALWVPGTREEVIEGIRLLGDAQRELVRAETEMNDAIGDITARYAP
LTESLKKRMAELQFGIQTWCEAHRDELTGNGKVKFANLTTGEVQWRNRPPSVSIRGADNV
IELLRRLGLERFIRVKEEINKDAILNEKEAVKNIPGISIKSDIEDFSIIPFEQDVQ