Protein Info for HEPCGN_20665 in Escherichia coli ECOR38

Name: yphG
Annotation: Uncharacterized protein YphG

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1093 PF17128: DUF5107" amino acids 39 to 324 (286 residues), 185.4 bits, see alignment E=3.3e-58 PF13432: TPR_16" amino acids 499 to 558 (60 residues), 19.8 bits, see alignment 2.4e-07 amino acids 542 to 602 (61 residues), 20.6 bits, see alignment 1.3e-07 amino acids 754 to 813 (60 residues), 19.1 bits, see alignment 4e-07

Best Hits

Swiss-Prot: 98% identical to YPHG_ECOLI: Uncharacterized protein YphG (yphG) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 100% identity to ect:ECIAI39_2752)

Predicted SEED Role

"Uncharacterized protein YphG, TPR-domain containing" in subsystem Unknown sugar utilization (cluster yphABCDEFG)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1093 amino acids)

>HEPCGN_20665 Uncharacterized protein YphG (Escherichia coli ECOR38)
MTPVKVWQERVEIPTYETGPQDIHPMFLENRVYQGSSGAVYPYGVTDTLSEQKTLKSWQA
VWLENDYIKVMILPELGGRVHRAWDKVKQRDFVYHNEVIKPALVGLLGPWISGGIEFNWP
QHHRPTTFMPVDFTLEAHDDGAQTVWVGETEPMHGLQVMTGFTLRPDRAALEIASRVYNG
NATPRHFLWWANPAVKGGEWHQSVFPPDVTAVFDHGKRAVSAFPIATGTYYKVDYSAGVD
ISRYKNVPVPTSYMAEKSQYDFVGAWCHDEDGGLLHVANHHIAPGKKQWSWGHSEFGQAW
DKSLTDNNGPYIELMTGIFADNQPDFTWLDAYEEKRFEQYFLPYHSLGMVQNASRDAVIK
LQRSERGIEWGLYAISPLNGYRLAIREIGKCNALLDDAVALMPATAIQGVLHGINPDRLT
IELSDADGNIILSYQEHQPQALPLPDVAKAPLAAQGITSTDEAWFIGQHLEQYHHASRSP
FDYYLRGVALDPLDYRCNLALAMLEYNRADFPQAVAYASQALKRAHALNKNPQCGQASLI
RASAYERQGQYQQAEEDFWRAVWSGNSKAGGYYGLARLAARNGHFDAGLDFCQQSLRACP
TNQEVLCLHNLLLVLSGRQDNARLQREKLLRDYPLNATLWWLNWFDGCSESALVQWRGLC
QGRDVNALMTAGQLINWGMPALAAEMLNALDCQRTLPLYLQASLLPKAERGELVAKAIDV
FPQFVRFPNTLEEVAALESIEECWFARHLLACFYYNKRSYGKAIALWQRCVEMSPEFADG
WRGLAIHAWNKQHDYELAARYLDNAYQLAPQDARLLFERDLLDKLSGATPEKRLARLENN
LEIALKRDDMTAELLNLWHLTGQADKAADILATRKFHPWEGGEGKITSQFILNQLLRAWQ
HLDAREPQQASELLHAALHYPENLSEGRLPGQTDNDIWFWQAICANAQGDQTEAMRCLRL
AATGDRTINIHSYYNDQPVDYLFWQGMALRLLGEQQIAQQLFSEMKQWAQEMAKTSIEAD
FFAVSQPDLLSLYGDLQQQHKEKCLMVAMLASAGLGEVAHYESARAELTAINPAWPKAAL
FTTVMPFIFNYVH