Protein Info for HEPCGN_19850 in Escherichia coli ECOR38

Name: norR
Annotation: nitric oxide reductase transcriptional regulator NorR

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 504 PF01590: GAF" amino acids 22 to 154 (133 residues), 50 bits, see alignment E=1.8e-16 PF13185: GAF_2" amino acids 25 to 155 (131 residues), 31 bits, see alignment E=1.2e-10 PF00158: Sigma54_activat" amino acids 187 to 353 (167 residues), 230 bits, see alignment E=5.7e-72 PF14532: Sigma54_activ_2" amino acids 188 to 358 (171 residues), 82.2 bits, see alignment E=1.7e-26 PF01078: Mg_chelatase" amino acids 193 to 327 (135 residues), 23.1 bits, see alignment E=1.7e-08 PF07728: AAA_5" amino acids 210 to 329 (120 residues), 24.9 bits, see alignment E=7e-09 PF00004: AAA" amino acids 211 to 343 (133 residues), 24.1 bits, see alignment E=1.7e-08

Best Hits

Swiss-Prot: 100% identical to NORR_ECO7I: Anaerobic nitric oxide reductase transcription regulator NorR (norR) from Escherichia coli O7:K1 (strain IAI39 / ExPEC)

KEGG orthology group: K12266, anaerobic nitric oxide reductase transcription regulator (inferred from 98% identity to sdy:SDY_2906)

Predicted SEED Role

"Anaerobic nitric oxide reductase transcription regulator NorR"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (504 amino acids)

>HEPCGN_19850 nitric oxide reductase transcriptional regulator NorR (Escherichia coli ECOR38)
MSFSVDVLANIAIELQRGIGHQDRFQRLITTLRQVLECDASALLRYDSRQFIPLAIDGLA
KDVLGRRFALEGHPRLEAIARAGDVVRFPADSELPDPYDGLIPGQESLKVHACVGLPLFA
GQNLIGALTLDGMQPDQFDVFSDEELRLIAALAAGALSNALLIEQLESQNMLPGDAAPFE
ALKETQMIGLSPGMTQLKKEIEIVAASDLNVLISGETGTGKELVAKAIHEASPRAVNPLV
YLNCAALPESVAESELFGHVKGAFTGAISNRSGKFEMADNGTLFLDEIGELSLALQAKLL
RVLQYGDIQRVGDDRSLRVDVRVLAATNRDLREEVLAGRFRADLFHRLSVFPLSVPPLRE
RGDDVILLAGYFCEQCRLRLGLSRVVLSSGARNLLQHYSFPGNVRELEHAIHRAVVLARA
TRSGDEVILEAQHFAFPEVTLPPPEAAAVPIVKQNLREATEAFQRETIRQALAQNHHNWA
ASARMLETDVANLHRLAKRLGLKD