Protein Info for HEPCGN_19050 in Escherichia coli ECOR38

Name: sctN
Annotation: type III secretion system ATPase SctN

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 435 TIGR01026: ATPase, FliI/YscN family" amino acids 6 to 434 (429 residues), 445.6 bits, see alignment E=9.3e-138 PF02874: ATP-synt_ab_N" amino acids 20 to 85 (66 residues), 20 bits, see alignment E=1.3e-07 PF00006: ATP-synt_ab" amino acids 146 to 354 (209 residues), 270.3 bits, see alignment E=1.8e-84 PF18269: T3SS_ATPase_C" amino acids 361 to 431 (71 residues), 69.2 bits, see alignment E=3.4e-23

Best Hits

Swiss-Prot: 64% identical to SPAL_SALTY: Probable ATP synthase SpaL (spaL) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

KEGG orthology group: K03224, ATP synthase in type III secretion protein SctN [EC: 3.6.3.14] (inferred from 100% identity to eum:ECUMN_3201)

Predicted SEED Role

No annotation

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.14

Use Curated BLAST to search for 3.6.3.14

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (435 amino acids)

>HEPCGN_19050 type III secretion system ATPase SctN (Escherichia coli ECOR38)
MVHAGMKKLKLLNKYSYLHSINGSLIEAELDDVSVGEVCEIYASWQANERIARAQVVGFR
NGKTLLNLIGSSVGLTRTAVLKPTGEQLTIQISDAFLGSVLNASGQIMERFVPDTPGERG
NLRLIDELPPSYQERRVINTPLETRIRVIDGVLTCGIGQRVGIFASAGCGKTVLMHMLVN
NTEADVFVIGLIGERGREVTECAESLKKSVNAAKCVLVYATSDFSSVDRCNAALMATTVA
EYFRDRGKRVVLFIDSMTRYARALRDMKLAAGEPPARRGYPASVFDSLPRLLERPGPTLK
GSITAFYTVLLEGEDESDPLGDEIRSILDGHIYLSRKLAGQGHYPAIDVLKSVSRVFGQV
TDEKHRDNAARVRKILTTLEDLQVFIDLGEYRAGQNAENDFAMNARPKLTNWLKQSVNEK
MPMSETLKELERIVK