Protein Info for HEPCGN_19010 in Escherichia coli ECOR38

Name: actS
Annotation: amidase activator ActS

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF01476: LysM
  • amino acids 42 to 84 (43 residues), 61.3 bits, 6.7e-21
• PF01551: Peptidase_M23
  • amino acids 144 to 237 (94 residues), 113.2 bits, E=5.4e-37

Best Hits

Swiss-Prot: 98% identical to YGER_ECOLI: Uncharacterized lipoprotein YgeR (ygeR) from Escherichia coli (strain K12)

KEGG orthology group: K12943, lipoprotein YgeR (inferred from 99% identity to ecm:EcSMS35_2998)

MetaCyc: 98% identical to amidase activator (Escherichia coli K-12 substr. MG1655)

Predicted SEED Role

"Uncharacterized lipoprotein YgeR precursor"

Protein Sequence (250 amino acids)

>HEPCGN_19010 amidase activator ActS (Escherichia coli ECOR38)
LSAGRLNKKSLGIVMLLSVGLLLAGCSGSKSSDTGTYSGSVYTVKRGDTLYRISRTTGTS
VKELARLNGISPPYTIEVGQKLKLGGAKSSSTRKSTAKSTTKTASVTPSSAVPKSSWPPV
GQRCWLWPTTGKVIMPYSTADGGNKGIDISAPRGTPIYAAGAGKVVYVGNQLRGYGNLIM
IKHSEDYITAYAHNDTMLVNNGQSVKAGQKIATMGSTDAASVRLHFQIRYRATAIDPLRY
LPPQGSKPKC