Protein Info for HEPCGN_17155 in Escherichia coli ECOR38

Name: agaE
Annotation: PTS N-acetylgalactosamine transporter subunit IID

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 292 transmembrane" amino acids 91 to 111 (21 residues), see Phobius details amino acids 132 to 157 (26 residues), see Phobius details amino acids 161 to 187 (27 residues), see Phobius details amino acids 205 to 226 (22 residues), see Phobius details amino acids 246 to 266 (21 residues), see Phobius details amino acids 272 to 290 (19 residues), see Phobius details PF03613: EIID-AGA" amino acids 36 to 292 (257 residues), 303.5 bits, see alignment E=5.8e-95

Best Hits

Swiss-Prot: 34% identical to PTRD_LACCA: PTS system sorbose-specific EIID component (sorD) from Lactobacillus casei

KEGG orthology group: K02747, PTS system, N-acetylgalactosamine-specific IID component (inferred from 99% identity to eoh:ECO103_3880)

MetaCyc: 37% identical to fructoselysine/glucoselysine PTS enzyme IID component (Salmonella enterica enterica serovar Typhimurium str. 14028S)
2.7.1.-; 2.7.1.-

Predicted SEED Role

"PTS system, N-acetylgalactosamine-specific IID component (EC 2.7.1.69)" in subsystem N-Acetyl-Galactosamine and Galactosamine Utilization (EC 2.7.1.69)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.1.69

Use Curated BLAST to search for 2.7.1.69

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (292 amino acids)

>HEPCGN_17155 PTS N-acetylgalactosamine transporter subunit IID (Escherichia coli ECOR38)
MASNQTTLPNVSENEETLLTGVNENVYEDQSIGAELTKKDINRVAWRSMLLQASFNYERM
QASGWLYGLLPALKKIHTNKRDLARAMKGHMGFFNTHPFLVTFVIGIILAMERSKQDVNS
IQSTKIAVGAPLGGIGDAMFWLTLLPICGGIGASLALQGSILGAVVFIVLFNVVHLGLRF
GLAHYAYRMGVAAIPLIKANTKKVGHAASIVGMTVIGALVATYVRLSTTLEITAGDAVVK
LQADVIDKLMPAFLPLVYTLTMFWLVRRGWSPLRLIAITVVLGIVGKFCHFL