Protein Info for HEPCGN_16045 in Escherichia coli ECOR38

Name: fic
Annotation: putative adenosine monophosphate-protein transferase Fic

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 PF02661: Fic" amino acids 58 to 152 (95 residues), 51.8 bits, see alignment E=6.2e-18

Best Hits

Swiss-Prot: 99% identical to FIC_ECOLI: Probable protein adenylyltransferase Fic (fic) from Escherichia coli (strain K12)

KEGG orthology group: K04095, cell filamentation protein (inferred from 99% identity to eco:b3361)

Predicted SEED Role

"Cell filamentation protein fic"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (200 amino acids)

>HEPCGN_16045 putative adenosine monophosphate-protein transferase Fic (Escherichia coli ECOR38)
MSDKFGEGRDPYLYPGLDIMRNRLNIHQQQRLEQAAYEMTALRAATIELGPLVRGLPHLR
TIHRQLYQDIFDWAGQLREVDIYQGDTPFCHFAYIEKEGNALMQDLEEEGYLVGLEKAKF
VERLAHYYCEINVLHPFRVGSGLAQRIFFEQLAIHAGYQLSWQGIEKEAWNQANQNGAMG
DLTALQMIFSKVVSEAGESE