Protein Info for HEPCGN_13785 in Escherichia coli ECOR38

Name: cbrA
Annotation: colicin M resistance protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 354 signal peptide" amino acids 1 to 20 (20 residues), see Phobius details PF01494: FAD_binding_3" amino acids 135 to 170 (36 residues), 25.1 bits, see alignment 1e-09

Best Hits

Swiss-Prot: 98% identical to CBRA_ECO24: Protein CbrA (cbrA) from Escherichia coli O139:H28 (strain E24377A / ETEC)

KEGG orthology group: None (inferred from 100% identity to ect:ECIAI39_4292)

Predicted SEED Role

"Uncharacterized protein YidS"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (354 amino acids)

>HEPCGN_13785 colicin M resistance protein (Escherichia coli ECOR38)
MEHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIR
DGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHD
SLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQW
FAEKHPVPFYSCIFDNAITDCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMNAFQFQ
FGKAVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSAEILRSVL
LKQPEKINATYWRATRKLRLKLYGKIVKSRCLTAPALRKWIMRSGVAHIPQLKD