Protein Info for HEPCGN_13010 in Escherichia coli ECOR38

Name: tnp-IS3
Annotation: IS3 family transposase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 301 PF13276: HTH_21" amino acids 55 to 104 (50 residues), 40.9 bits, see alignment 2.9e-14 PF00665: rve" amino acids 124 to 227 (104 residues), 68 bits, see alignment E=1.1e-22 PF13683: rve_3" amino acids 216 to 281 (66 residues), 63.3 bits, see alignment E=2.2e-21

Best Hits

Swiss-Prot: 97% identical to IND12_ECOLI: Transposase InsD for insertion element IS2-12 (JW5933) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 97% identity to ebw:BWG_0249)

Predicted SEED Role

"Mobile element protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (301 amino acids)

>HEPCGN_13010 IS3 family transposase (Escherichia coli ECOR38)
VDSARALIARGWGVSLVSRCLRVSRAQLHVILRRTDDWMDGRRSRHTDDTDVLLRIHHVI
GELPTYGYRRVWALLRRQAELDGMPAINAKRVYRIMRQNALLLERKPAVPPSKRAHTGRV
AVKESNQRWCSDGFEFRCDNGEKLRVTFVLDCCDREALHWAVTTGGFNSETVQDVMLGAV
ERRFGNELPASPVEWLTDNGSCYRANETRQFARMLGLEPKSTAVRSPESNGIAESFVKTI
KRDYISVMPKPDGLTAAKNLAEAFEHYNEWHPHSALGYRSPREYLRQQASNGLSDNRCLE
I