Protein Info for HEPCGN_12060 in Escherichia coli ECOR38

Name: rbsK
Annotation: ribokinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 405 PF08220: HTH_DeoR" amino acids 6 to 59 (54 residues), 63 bits, see alignment 3.4e-21 PF08279: HTH_11" amino acids 6 to 47 (42 residues), 28.6 bits, see alignment 2.1e-10 PF00294: PfkB" amino acids 100 to 389 (290 residues), 239 bits, see alignment E=1.5e-74 TIGR02152: ribokinase" amino acids 101 to 395 (295 residues), 311.4 bits, see alignment E=3.2e-97 PF08543: Phos_pyr_kin" amino acids 259 to 383 (125 residues), 62.1 bits, see alignment E=1.1e-20

Best Hits

KEGG orthology group: None (inferred from 100% identity to ect:ECIAI39_4374)

Predicted SEED Role

"Ribokinase (EC 2.7.1.15)" in subsystem D-ribose utilization or Deoxyribose and Deoxynucleoside Catabolism (EC 2.7.1.15)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.1.15

Use Curated BLAST to search for 2.7.1.15

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (405 amino acids)

>HEPCGN_12060 ribokinase (Escherichia coli ECOR38)
MFGKERQRQILAYLNKHERATVNQLAILFSVSKETIRNDLNLLAEQGGVERCHGGAIILR
RIFHSQPVNNVGTSIEKFLNQVNWRKNSMTNKKGKIMISKVCILGSFNVDIIAKVDRFPK
SGESILASNTIIGPGGKGANQAMAASKCPVQVHFVGKVGNDHFGQMAHDHLSSSDIRSFT
LYQDEEHKTGSAIIYVSEPAGENKIAIYSGANQYITEAEVASIAGELTDAKIFLTQLENN
FEATTLALNMAHRSGVKTILNPAPYSDQAKECLQYVDYLTPNETEASLMSGVEINDIESA
KEAAQTIKSLGAKNIIITMGSQGALVYDGEQFTHIPALKAVSIDTTGAGDAFNGAFAAAI
AQGQPLLSAAKFASAFAFLAVEREGASNMPEYEAVLSRLAQYERK