Protein Info for HEPCGN_11650 in Escherichia coli ECOR38

Name: malG
Annotation: maltose ABC transporter permease MalG

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 296 transmembrane" amino acids 12 to 38 (27 residues), see Phobius details amino acids 89 to 110 (22 residues), see Phobius details amino acids 122 to 144 (23 residues), see Phobius details amino acids 150 to 175 (26 residues), see Phobius details amino acids 206 to 228 (23 residues), see Phobius details amino acids 258 to 281 (24 residues), see Phobius details PF00528: BPD_transp_1" amino acids 111 to 286 (176 residues), 60.3 bits, see alignment E=1e-20

Best Hits

Swiss-Prot: 100% identical to MALG_SHIFL: Maltose/maltodextrin transport system permease protein MalG (malG) from Shigella flexneri

KEGG orthology group: K10110, maltose/maltodextrin transport system permease protein (inferred from 100% identity to eco:b4032)

MetaCyc: 100% identical to maltose ABC transporter membrane subunit MalG (Escherichia coli K-12 substr. MG1655)
ABC-16-RXN [EC: 7.5.2.1]; 7.5.2.1 [EC: 7.5.2.1]; 7.5.2.1 [EC: 7.5.2.1]

Predicted SEED Role

"Maltose/maltodextrin ABC transporter, permease protein MalG" in subsystem Maltose and Maltodextrin Utilization

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.5.2.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (296 amino acids)

>HEPCGN_11650 maltose ABC transporter permease MalG (Escherichia coli ECOR38)
MAMVQPKSQKARLFITHLLLLLFIAAIMFPLLMVVAISLRQGNFATGSLIPEQISWDHWK
LALGFSVEQADGRITPPPFPVLLWLWNSVKVAGISAIGIVALSTTCAYAFARMRFPGKAT
LLKGMLIFQMFPAVLSLVALYALFDRLGEYIPFIGLNTHGGVIFAYLGGIALHVWTIKGY
FETIDSSLEEAAALDGATPWQAFRLVLLPLSVPILAVVFILSFIAAITEVPVASLLLRDV
NSYTLAVGMQQYLNPQNYLWGDFAAAAVMSALPITIVFLLAQRWLVNGLTAGGVKG