Protein Info for HEPCGN_09860 in Escherichia coli ECOR38

Annotation: MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 229 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details transmembrane" amino acids 48 to 70 (23 residues), see Phobius details amino acids 82 to 103 (22 residues), see Phobius details amino acids 110 to 127 (18 residues), see Phobius details amino acids 134 to 154 (21 residues), see Phobius details amino acids 166 to 188 (23 residues), see Phobius details amino acids 195 to 214 (20 residues), see Phobius details PF07690: MFS_1" amino acids 82 to 223 (142 residues), 37 bits, see alignment E=1e-13

Best Hits

Predicted SEED Role

"Homolog of fucose/glucose/galactose permeases" in subsystem Hexose Phosphate Uptake System

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (229 amino acids)

>HEPCGN_09860 MFS transporter (Escherichia coli ECOR38)
MILVVVMVLFLLTRFPTCKVAQTSHYKRPSAMDTLRYLARNPRFRRGIVAQFLYVGMQVA
VWSFTIRLALELGDINERDASNFMVYSFACFFIGKFIANILMTCFNPEKVLILYSVIGAL
FLAYVALAPSFSAVYVAVLVSVLFGPCWATIYAGTLDTVDNEHTEMAGAVIVMAIVGAAV
VPAIQGYIADMFHSLQLSFLVSMLCFVYVGVYFWRESKVRTALAEVTAS