Protein Info for HEPCGN_09765 in Escherichia coli ECOR38

Name: virK
Annotation: virulence factor VirK

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 316 transmembrane" amino acids 36 to 51 (16 residues), see Phobius details PF04393: DUF535" amino acids 26 to 298 (273 residues), 301.7 bits, see alignment E=2.6e-94

Best Hits

KEGG orthology group: K09824, hypothetical protein (inferred from 100% identity to ecq:ECED1_5142)

Predicted SEED Role

"Virulence factor VirK"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (316 amino acids)

>HEPCGN_09765 virulence factor VirK (Escherichia coli ECOR38)
MFSISNLSFIGFLKRIIFSSDSLPGKWEHRKFRFMYILRCSINPVVSIRYYYELRSLPCI
EDILAIHPTLPARIHRPYLHKGGRAWTRGQYILEHYRFVQNLPEKYSKFLFPQKSVSLVQ
FIGKDGENFDIQCSPSGFDREGELMLSLFYNKTVIARLTFSVILTQNGHIAFIGGLQGAP
KNTGPDVIRCATRACYGIFPKRIIFEAFCALMKACNISECLAVSEHSHVFRQLRYWYQKR
KTFVAVYSDFWESVAGKTCDDWYRLPTQVIRKPLSDIASKKRSEYRKRYALLDYIHETTI
RSLDAYPVHSEHQNLN