Protein Info for HEPCGN_08805 in Escherichia coli ECOR38

Name: djlA
Annotation: co-chaperone DjlA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 271 transmembrane" amino acids 6 to 31 (26 residues), see Phobius details PF05099: TerB" amino acids 62 to 170 (109 residues), 32.8 bits, see alignment E=7.6e-12 PF00226: DnaJ" amino acids 208 to 267 (60 residues), 40.8 bits, see alignment E=2e-14

Best Hits

Swiss-Prot: 100% identical to DJLA_SHIFL: Co-chaperone protein DjlA (djlA) from Shigella flexneri

KEGG orthology group: K05801, DnaJ like chaperone protein (inferred from 100% identity to eco:b0055)

Predicted SEED Role

"DnaJ-like protein DjlA"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (271 amino acids)

>HEPCGN_08805 co-chaperone DjlA (Escherichia coli ECOR38)
MQYWGKIIGVAVALLMGGGFWGVVLGLLIGHMFDKARSRKMAWFANQRERQALFFATTFE
VMGHLTKSKGRVTEADIHIASQLMDRMNLHGASRTAAQNAFRVGKSDNYPLREKMRQFRS
VCFGRFDLIRMFLEIQIQAAFADGSLHPNERAVLYVIAEELGISRAQFDQFLRMMQGGAQ
FGGGYQQQSGGGNWQQAQRGPTLEDACNVLGVKPTDDATTIKRAYRKLMSEHHPDKLVAK
GLPPEMMEMAKQKAQEIQQAYELIKQQKGFK