Protein Info for HEPCGN_08210 in Escherichia coli ECOR38

Name: dgt
Annotation: dGTPase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR01353: putative dGTPase
  • amino acids 30 to 502 (473 residues), 497.7 bits, E=1.7e-153
• PF01966: HD
  • amino acids 66 to 146 (81 residues), 31.5 bits, E=1.9e-11

Best Hits

Swiss-Prot: 100% identical to DGTP_ECO8A: Deoxyguanosinetriphosphate triphosphohydrolase (dgt) from Escherichia coli O8 (strain IAI1)

KEGG orthology group: K01129, dGTPase [EC: 3.1.5.1] (inferred from 100% identity to eco:b0160)

MetaCyc: 100% identical to dGTP triphosphohydrolase (Escherichia coli K-12 substr. MG1655)
dGTPase. [EC: 3.1.5.1]

Predicted SEED Role

No annotation

KEGG Metabolic Maps

• Purine metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.1.5.1

Protein Sequence (505 amino acids)

>HEPCGN_08210 dGTPase (Escherichia coli ECOR38)
MAQIDFRKKINWHRRYRSPQGVKTEHEILRIFESDRGRIINSPAIRRLQQKTQVFPLERN
AAVRTRLTHSMEVQQVGRYIAKEILSRLKELKLLEAYGLDELTGPFESIVEMSCLMHDIG
NPPFGHFGEAAINDWFRQRLHPEDAESQPLTDDRCSVAALRLRDGEEPLNELRRKIRQDL
CHFEGNAQGIRLVHTLMRMNLTWAQVGGILKYTRPAWWRGETPETHHYLMKKPGYYLSEE
AYIARLRKELNLALYSRFPLTWIMEAADDISYCVADLEDAVEKRIFTVEQLYHHLHEAWG
QHEKGSLFSLVVENAWEKSRSNSLSRSTEDQFFMYLRVNTLNKLVPYAAQRFIDNLPAIF
AGTFNHALLEDASECSDLLKLYKNVAVKHVFSHPDVEQLELQGYRVISGLLEIYRPLLSL
SLSDFTELVEKERVKRFPIESRLFHKLSTRHRLAYVEAVSKLPSDSPEFPLWEYYYRCRL
LQDYISGMTDLYAWDEYRRLMAVEQ