Protein Info for HEPCGN_07815 in Escherichia coli ECOR38

Name: rtcB
Annotation: RNA ligase RtcB family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 379 TIGR03073: release factor H-coupled RctB family protein" amino acids 13 to 367 (355 residues), 621.1 bits, see alignment E=2.8e-191 PF01139: RtcB" amino acids 29 to 97 (69 residues), 47.2 bits, see alignment E=1e-16 amino acids 106 to 372 (267 residues), 201.9 bits, see alignment E=1.1e-63

Best Hits

KEGG orthology group: None (inferred from 100% identity to ect:ECIAI39_0416)

Predicted SEED Role

"Protein with similarity to RtcB" in subsystem RNA 3'-terminal phosphate cyclase

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (379 amino acids)

>HEPCGN_07815 RNA ligase RtcB family protein (Escherichia coli ECOR38)
MGKYIRPLSDAVLTIASDDLWIESSAIQQLHTTANLPDMQRVVGMPDLHPGRGYPIGAAF
FSVGRFYPALVGNDIGCGMALWQTDIFARKYNADKFEKRLSALDDVAEESWLEENLPSAL
AQHPWRSSLGSIGGGNHFAELQQVDQIIDAELFALTGLDAQHLQLLVHSGSRGLGQSILQ
RHIASFSHHGLPEGSDDALSYIVEHDDALAFARINRQMIALRIMQQVKATGSPVLDVAHN
FVSACQIGDQQGWLHRKGATPDDNGLVIIPGSRGDYSWLVKPVANEKTLHSLAHGAGRKW
GRTECKGRLAAKYTATQLSRTELGSRVICRDKQLIFEEAPQAYKSTESVVQCLVQAGLII
PVARLRPVLTLKNNGGKKG