Protein Info for HEPCGN_07325 in Escherichia coli ECOR38

Name: tauD
Annotation: taurine dioxygenase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00528: BPD_transp_1
  • amino acids 1 to 83 (83 residues), 38.5 bits, E=1.1e-13
• PF02668: TauD
  • amino acids 82 to 331 (250 residues), 236.9 bits, E=3.9e-74

Best Hits

KEGG orthology group: K03119, taurine dioxygenase [EC: 1.14.11.17] (inferred from 99% identity to ect:ECIAI39_0313)

Predicted SEED Role

"Alpha-ketoglutarate-dependent taurine dioxygenase (EC 1.14.11.17)" in subsystem Alkanesulfonate assimilation or Taurine Utilization (EC 1.14.11.17)

MetaCyc Pathways

• taurine degradation IV (1/1 steps found)
• superpathway of taurine degradation (2/6 steps found)

KEGG Metabolic Maps

• Taurine and hypotaurine metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.14.11.17

Protein Sequence (342 amino acids)

>HEPCGN_07325 taurine dioxygenase (Escherichia coli ECOR38)
VLWFVILPGALPEILTGLRIGLGVGWSTLVAAELIAATRGLGFMVQSAGEFLATDVVLAG
IAVIAIIAFLLELGLRALQRRLTRPLSDNQFEQLYHAVLRHQVVFLRDQAITPQQQRALA
QRFGELHIHPVYPHAEGVDEIIVLDTHNDNPPDNDNWHTDVTFIETPPAGAILAAKELPS
TGGDTLWTSGIAAYEALSVPFRQLLSGLRAEHDFRKSFPEYKYRKTEEEHQRWREAVAKN
PPLLHPVVRTHPVSGKQALFVNEGFTTRIVDVSEKESEALLSFLFAHITKPEFQVRWRWQ
PNDIAIWDNRVTQHYANADYLPQRRIMHRATILGDKPFYRAG