Protein Info for HEPCGN_06265 in Escherichia coli ECOR38

Name: tnp-IS600
Annotation: IS3 family IS600 transposase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 272 PF13276: HTH_21" amino acids 27 to 83 (57 residues), 51.2 bits, see alignment E=2.4e-17 PF00665: rve" amino acids 107 to 205 (99 residues), 91.3 bits, see alignment E=8.5e-30 PF13683: rve_3" amino acids 194 to 260 (67 residues), 52.3 bits, see alignment E=7.7e-18 PF13333: rve_2" amino acids 212 to 266 (55 residues), 50.7 bits, see alignment E=3.3e-17

Best Hits

Swiss-Prot: 98% identical to YIS2_SHISO: Insertion element IS600 uncharacterized 31 kDa protein from Shigella sonnei

KEGG orthology group: None (inferred from 99% identity to ecc:c3575)

Predicted SEED Role

"Mobile element protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (272 amino acids)

>HEPCGN_06265 IS3 family IS600 transposase (Escherichia coli ECOR38)
MCQVFGVSRSGYYNWVQHEPSDRKQSDERLKLEIKVAHIRTRETYGTRRLQTELAENGII
VGRDRLARLRKELRLRCKQKRKFRATTNPNHNLPVAPNLLNQTFTPTAPNQVWVADLTYV
ATQEGWLYLAGIKDVYTCEIVGYAMGERMTKELTGKALFMALRSQRPPAGLIHHSDRGSQ
YCAYDYRVIQEQFGLKTSMSRKGNCYDNAPMESFWGTLKNESLSHYRFNNRDEAISVIRE
YIEIFYNRQRRHSRLGNISPAAFREKYHQMAA