Protein Info for HEPCGN_06145 in Escherichia coli ECOR38

Name: dmsB
Annotation: dimethylsulfoxide reductase subunit B

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 198 TIGR02951: dimethylsulfoxide reductase, chain B" amino acids 4 to 156 (153 residues), 249.8 bits, see alignment E=5.9e-79 PF12797: Fer4_2" amino acids 7 to 25 (19 residues), 25.1 bits, see alignment (E = 4.7e-09) amino acids 84 to 104 (21 residues), 26.5 bits, see alignment (E = 1.7e-09) PF12800: Fer4_4" amino acids 12 to 25 (14 residues), 16.4 bits, see alignment (E = 3.7e-06) amino acids 90 to 105 (16 residues), 15.5 bits, see alignment (E = 7.4e-06) PF13247: Fer4_11" amino acids 52 to 146 (95 residues), 102.6 bits, see alignment E=4.8e-33 PF12838: Fer4_7" amino acids 60 to 106 (47 residues), 27.9 bits, see alignment 1e-09 PF12837: Fer4_6" amino acids 84 to 107 (24 residues), 32.2 bits, see alignment (E = 2.9e-11) PF00037: Fer4" amino acids 85 to 107 (23 residues), 31 bits, see alignment (E = 6.5e-11)

Best Hits

Swiss-Prot: 96% identical to YNFG_ECOLI: Probable anaerobic dimethyl sulfoxide reductase chain YnfG (ynfG) from Escherichia coli (strain K12)

KEGG orthology group: K07311, Tat-targeted selenate reductase subunit YnfG (inferred from 96% identity to eco:b1589)

MetaCyc: 96% identical to putative oxidoreductase YnfG (Escherichia coli K-12 substr. MG1655)
Selenate reductase. [EC: 1.97.1.9]

Predicted SEED Role

No annotation

Isozymes

Compare fitness of predicted isozymes for: 1.97.1.9

Use Curated BLAST to search for 1.97.1.9

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (198 amino acids)

>HEPCGN_06145 dimethylsulfoxide reductase subunit B (Escherichia coli ECOR38)
MTTQYGFFIDSSRCTGCKTCELACKDFKDLGPEVSFRRIYEYAGGVWHQNVFAYYLSISC
NHCDDPACTKVCPSGAMHKREDGFVVVDEDVCIGCRYCHMACPYGAPQYNAEKGHMTKCD
GCYSRVAEGKQPICVESCPLRALEFGPIEELRQKHGTLAAVAPLPRAHFTKPNIVIKPNA
NSRPTGDTTGYLANPEKV