Protein Info for HEPCGN_05455 in Escherichia coli ECOR38

Annotation: Integration host factor subunit alpha

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 25 50 75 99 TIGR00987: integration host factor, alpha subunit" amino acids 2 to 97 (96 residues), 182 bits, see alignment E=1e-58 PF00216: Bac_DNA_binding" amino acids 3 to 91 (89 residues), 106.6 bits, see alignment E=6.3e-35 PF18291: HU-HIG" amino acids 7 to 94 (88 residues), 29 bits, see alignment E=9.7e-11

Best Hits

Swiss-Prot: 100% identical to IHFA_ECODH: Integration host factor subunit alpha (ihfA) from Escherichia coli (strain K12 / DH10B)

KEGG orthology group: K04764, integration host factor subunit alpha (inferred from 100% identity to eco:b1712)

Predicted SEED Role

"Integration host factor alpha subunit" in subsystem DNA structural proteins, bacterial

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (99 amino acids)

>HEPCGN_05455 Integration host factor subunit alpha (Escherichia coli ECOR38)
MALTKAEMSEYLFDKLGLSKRDAKELVELFFEEIRRALENGEQVKLSGFGNFDLRDKNQR
PGRNPKTGEDIPITARRVVTFRPGQKLKSRVENASPKDE