Protein Info for HEPCGN_05005 in Escherichia coli ECOR38
Name: yeaW
Annotation: carnitine monooxygenase subunit YeaW
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 100% identical to CNTA_ECOLI: Carnitine monooxygenase oxygenase subunit (yeaW) from Escherichia coli (strain K12)
KEGG orthology group: K00517, [EC: 1.14.-.-] (inferred from 100% identity to eco:b1802)MetaCyc: 100% identical to carnitine monooxygenase subunit YeaW (Escherichia coli K-12 substr. MG1655)
RXN-18258 [EC: 1.14.13.239]; 1.14.13.239 [EC: 1.14.13.239]; 1.14.13.239 [EC: 1.14.13.239]
Predicted SEED Role
"Putative dioxygenase, alpha subunit (EC 1.-.-.-); Choline monooxygenase, alpha subunit (EC 1.14.15.7)" (EC 1.-.-.-, EC 1.14.15.7)
MetaCyc Pathways
- glycine betaine biosynthesis III (plants) (3/3 steps found)
- L-carnitine degradation II (2/3 steps found)
KEGG Metabolic Maps
- 1,4-Dichlorobenzene degradation
- Alkaloid biosynthesis I
- Ascorbate and aldarate metabolism
- Benzoxazinone biosynthesis
- Biosynthesis of phenylpropanoids
- Biosynthesis of plant hormones
- Biosynthesis of steroids
- Biosynthesis of terpenoids and steroids
- Brassinosteroid biosynthesis
- Carotenoid biosynthesis - General
- Diterpenoid biosynthesis
- Glycine, serine and threonine metabolism
- Insect hormone biosynthesis
- Limonene and pinene degradation
- Naphthalene and anthracene degradation
- Nucleotide sugars metabolism
- Phenylpropanoid biosynthesis
- Porphyrin and chlorophyll metabolism
- Puromycin biosynthesis
- Sphingolipid metabolism
- Trinitrotoluene degradation
- Tryptophan metabolism
- Ubiquinone and menaquinone biosynthesis
- alpha-Linolenic acid metabolism
- gamma-Hexachlorocyclohexane degradation
Isozymes
Compare fitness of predicted isozymes for: 1.-.-.-, 1.14.-.-
Use Curated BLAST to search for 1.-.-.- or 1.14.-.- or 1.14.13.239 or 1.14.15.7
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (374 amino acids)
>HEPCGN_05005 carnitine monooxygenase subunit YeaW (Escherichia coli ECOR38) MSNLSPDFVLPENFCANPQEAWTIPARFYTDQNAFEHEKENVFAKSWICVAHSSELANAN DYVTREIIGESIVLVRGRDKVLRAFYNVCPHRGHQLLSGEGKAKNVITCPYHAWAFKLDG NLAHARNCENVANFDSDKAQLVPVRLDEYAGFVFINMDPNATSVEDQLPGLGAKVLEACP EVHDLKLAARFTTRTPANWKNIVDNYLECYHCGPAHPGFSDSVQVDRYWHTMHGNWTLQY GFAKPSEQSFKFEEGTDAAFHGFWLWPCTMLNVTPIKGMMTVIYEFPVDSETTLQNYDIY FTNEELTDEQKSLIEWYRDVFRPEDLRLVESVQKGLKSRGYRGQGRIMADSSGSGISEHG IAHFHNLLAQVFKD