Protein Info for HEPCGN_04140 in Escherichia coli ECOR38

Name: fliZ
Annotation: flagella biosynthesis regulatory protein FliZ

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 183 TIGR03823: flagellar regulatory protein FliZ" amino acids 1 to 167 (167 residues), 303.2 bits, see alignment E=2e-95 PF02899: Phage_int_SAM_1" amino acids 90 to 163 (74 residues), 52.3 bits, see alignment E=2.9e-18

Best Hits

Swiss-Prot: 97% identical to FLIZ_ECOLI: Regulator of sigma S factor FliZ (fliZ) from Escherichia coli (strain K12)

KEGG orthology group: K02425, FliZ protein (inferred from 97% identity to eco:b1921)

Predicted SEED Role

"Flagellar biosynthesis protein FliZ" in subsystem Flagellum

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (183 amino acids)

>HEPCGN_04140 flagella biosynthesis regulatory protein FliZ (Escherichia coli ECOR38)
MMVQHLKRRPLSRYLKDFKHSQTHCAHCRKLLDRITLVRDGKIVNKIEISRLDTLLDENG
WQVEQQSWAALCRFCGDLHCKTQSDFFDIIGFKQFLFEQTEMSPGTVREYVVRLRRLGNH
LHEQNISLDQLQDGFLDEILAPWLPSTSTNNYRIALRKYQHYQRQTCTGLVQKSSSQPAS
DIY