Protein Info for HEPCGN_02025 in Escherichia coli ECOR38

Name: rcdA
Annotation: DNA-binding transcriptional regulator RcdA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 178 PF00440: TetR_N" amino acids 13 to 59 (47 residues), 31 bits, see alignment E=1.8e-11 PF17940: TetR_C_31" amino acids 82 to 177 (96 residues), 37.7 bits, see alignment E=2e-13

Best Hits

Swiss-Prot: 99% identical to RCDA_ECOLI: HTH-type transcriptional regulator RcdA (rcdA) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 99% identity to eco:b0846)

Predicted SEED Role

"Transcriptional regulator, TetR family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (178 amino acids)

>HEPCGN_02025 DNA-binding transcriptional regulator RcdA (Escherichia coli ECOR38)
MRRANDPQRREKIIQATLEAVKLYGIHAVTHRKIATLAGVPLGSMTYYFSGIDELLLEAF
SRFTEIMSRQYQAFFSDVSDAQGACQAITDMIYSSQVATPDNMELMYQLYALASRKPLLK
TVMQNWMQRSQQTLEQWFEPGTARALDAFIEGMTLHFVTDRKPLSREEILRMVERVAG