Protein Info for PS417_05030 in Pseudomonas simiae WCS417

Annotation: major facilitator transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 455 signal peptide" amino acids 1 to 44 (44 residues), see Phobius details transmembrane" amino acids 59 to 78 (20 residues), see Phobius details amino acids 90 to 109 (20 residues), see Phobius details amino acids 115 to 135 (21 residues), see Phobius details amino acids 147 to 170 (24 residues), see Phobius details amino acids 176 to 198 (23 residues), see Phobius details amino acids 259 to 279 (21 residues), see Phobius details amino acids 295 to 315 (21 residues), see Phobius details amino acids 322 to 342 (21 residues), see Phobius details amino acids 348 to 371 (24 residues), see Phobius details amino acids 385 to 408 (24 residues), see Phobius details amino acids 414 to 433 (20 residues), see Phobius details PF07690: MFS_1" amino acids 28 to 289 (262 residues), 124.3 bits, see alignment E=1.1e-39 amino acids 262 to 442 (181 residues), 69.9 bits, see alignment E=3.9e-23 PF06779: MFS_4" amino acids 45 to 217 (173 residues), 30.8 bits, see alignment E=4.2e-11 PF00083: Sugar_tr" amino acids 58 to 425 (368 residues), 84.4 bits, see alignment E=1.7e-27

Best Hits

KEGG orthology group: K08195, MFS transporter, AAHS family, 4-hydroxybenzoate transporter (inferred from 93% identity to pfs:PFLU1028)

Predicted SEED Role

"4-hydroxybenzoate transporter" in subsystem Cinnamic Acid Degradation or Gentisare degradation or Phenylpropanoid compound degradation or Salicylate and gentisate catabolism or p-Hydroxybenzoate degradation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7U023 at UniProt or InterPro

Protein Sequence (455 amino acids)

>PS417_05030 major facilitator transporter (Pseudomonas simiae WCS417)
MHNQLASFRAALDARPVSRYQWLILLLLALLLVTDGYDAQVLGYVVPALAQDWGLEKAAF
GPVFSANLLGLTLGSLLVTPLADRFGVRRILLGCVLIYASLTVLMVFANSLTTLMAARFI
CGIGMGGAMPSAMALMSEYSPPRLRTLMVTLAACGFSFGGAAGGFVAAGFIEGFGWQAVF
LAGGVTPLLLFPFLVWLLPESLPRLLRDAPPYARLQNVTSRMLPGWQPPLATEAENQQEQ
GSKLTVVELFRNGYARPTLLIWSTFFVSLILLYFMISWLPSLLLESGLALKEANLVTSMF
LFAGTLGAIAMAWFADRLKRKVRLLSGVLAAAAVCTLLLGLNHDNPRYLVACVVAAGFCI
IGGQLTLNAFASNFYPAHVRATGTGWALGVGRFGSILGPLFGSLLLAMHIPVQQIFFFCA
IPAVIAALLIIQVRSPEAEGSKSPLAGDPLKAPQA