Protein Info for GFF990 in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

Annotation: FIG00637933: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 413 transmembrane" amino acids 12 to 31 (20 residues), see Phobius details amino acids 51 to 71 (21 residues), see Phobius details amino acids 83 to 102 (20 residues), see Phobius details amino acids 108 to 129 (22 residues), see Phobius details amino acids 141 to 163 (23 residues), see Phobius details amino acids 171 to 190 (20 residues), see Phobius details amino acids 219 to 244 (26 residues), see Phobius details amino acids 257 to 276 (20 residues), see Phobius details amino acids 286 to 307 (22 residues), see Phobius details amino acids 313 to 338 (26 residues), see Phobius details amino acids 350 to 371 (22 residues), see Phobius details amino acids 377 to 398 (22 residues), see Phobius details PF07690: MFS_1" amino acids 26 to 355 (330 residues), 110.2 bits, see alignment E=1.1e-35 PF00083: Sugar_tr" amino acids 50 to 194 (145 residues), 36.8 bits, see alignment E=2.3e-13

Best Hits

Swiss-Prot: 100% identical to MDTM_SALTI: Multidrug resistance protein MdtM (mdtM) from Salmonella typhi

KEGG orthology group: None (inferred from 100% identity to seg:SG4347)

MetaCyc: 86% identical to multidrug efflux pump / bile salt:H+ antiporter / Na+:H+ antiporter / K+:H+ antiporter (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-129; TRANS-RXN-336; TRANS-RXN-44; TRANS-RXN0-588; TRANS-RXN0-589

Predicted SEED Role

"FIG00637933: hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (413 amino acids)

>GFF990 FIG00637933: hypothetical protein (Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868)
MQRIIQFFSQRATTLFFPMALILYDFAAYLTTDLIQPGIINVVRDFNADVSLAPASVSLY
LAGGMALQWLLGPLSDRIGRRPVLIAGALIFTLACAATLLTTSMTQFLVARFVQGTSICF
IATVGYVTVQEAFGQTKAIKLMAIITSIVLVAPVIGPLSGAALMHFVHWKVLFGIIAVMG
LLALCGLLLAMPETVQRGAVPFSAVSVLRDFRNVFRNPIFLTGAATLSLSYIPMMSWVAV
SPVILIDAGGMSTSQFAWAQVPVFGAVIVANMIVVRLVKDPTRPRFIWRAVPIQLSGLAT
LLLGNLLLPHVWLWSVLGTSLYAFGIGMIFPTLFRFTLFSNNLPKGTVSASLNMVILTVM
AVSVEVGRWLWFHGGRLPFHLLAAVAGVIVVFTLATLLQRVRQHEAAELAAEK