Protein Info for GFF980 in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

Annotation: Tryptophanyl-tRNA synthetase (EC 6.1.1.2)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR00233: tryptophan--tRNA ligase
  • amino acids 6 to 331 (326 residues), 228.7 bits, E=5.8e-72
• PF00579: tRNA-synt_1b
  • amino acids 6 to 285 (280 residues), 171.3 bits, E=1.5e-54

Best Hits

Swiss-Prot: 55% identical to SYW_CLOLO: Tryptophan--tRNA ligase (trpS) from Clostridium longisporum

KEGG orthology group: K01867, tryptophanyl-tRNA synthetase [EC: 6.1.1.2] (inferred from 99% identity to stt:t4557)

Predicted SEED Role

"Tryptophanyl-tRNA synthetase (EC 6.1.1.2)" (EC 6.1.1.2)

MetaCyc Pathways

• tRNA charging (21/21 steps found)

KEGG Metabolic Maps

• Aminoacyl-tRNA biosynthesis
• Tryptophan metabolism

Isozymes

Compare fitness of predicted isozymes for: 6.1.1.2

Use Curated BLAST to search for 6.1.1.2

Protein Sequence (337 amino acids)

>GFF980 Tryptophanyl-tRNA synthetase (EC 6.1.1.2) (Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868)
MNTLPIILTGDRPTGSLHLGHYVGSLRQRVALQQDHQQYVLIADLQGLTDNGSNPQKIRD
NIPQVLADYLAVGIDPTLTTICLQSALPALAELTVLYMNIVTVARVERNPTVKNEIAQKG
FTRSLPVGFMAYPISQAADITAFKAEMVPVGDDQLPMIEQTNEIVHKMNSLFSSPVLRPC
QALLSDTGRLPGIDGSAKMSKSLGNTLLLSASEETIHRAVSAMYTDPNHLKISDPGKIEG
NVVFTWLDAFHPDKAKVAAMKAHYQQGGLGDRVCKNELETCLQELIAPIRERRATFIADK
GMLMELLKKGSERAHEVTQKTLQEVKRGLGLPTLFQV