Protein Info for GFF944 in Sphingobium sp. HT1-2

Annotation: Large protein containing transglutaminase-like domain

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1114 PF08379: Bact_transglu_N" amino acids 6 to 81 (76 residues), 85.7 bits, see alignment 4.3e-28 PF01841: Transglut_core" amino acids 142 to 245 (104 residues), 55.3 bits, see alignment E=1.1e-18 PF09899: DUF2126" amino acids 275 to 1108 (834 residues), 1290.5 bits, see alignment E=0

Best Hits

KEGG orthology group: None (inferred from 62% identity to avi:Avi_3752)

Predicted SEED Role

"Large protein containing transglutaminase-like domain"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1114 amino acids)

>GFF944 Large protein containing transglutaminase-like domain (Sphingobium sp. HT1-2)
MLKAALHHLTAYRYSRPIRLGPQVIRLRPAPHSRTKIPNYALKIEPANHFLNWQQDPHGN
WLARIVFPDPVDHFSIEVDLLADLDIINPFDFFVEPYAENYPFSYDEQLETDLAAYYDVE
MQGPLFEELVAQHATFEGRTIDFLVDVNSKLQQRIGYVIRMETGVQSPEETLDIGTGSCR
DSAWLLVQLLRRLGFAARFVSGYSIQLVADVEPIEGPKGVTQDVVDLHAWAEAYVPGAGW
IALDATSGMFAGEGHIPLCATPHYRSAAPISGMAEPAEVDFNFAMNVSRIAEAVRITKPF
TEGRWASLMALGEQVDADLIAQDVRLTTGGEPTFVAVDDPQAGEWNGDAVGPTKAGYADR
LIRRLRDRFAPGALLHHGQGKWYPGESLPRWGYSIYWRADGVPIWRDAGLIAGEPEAGDT
TITAEDAGRFLTAMADGLGVETDFVQPVFEDALAWSVKEAELPANTEPGDPKFDNPEERS
RMVRAFEGGLSKTVGYVLPIQRWQTQASAPRWQSEVWKVRRKALFAVPGDSALGYRLPLG
TLPYVPPSDFPYIHPQDTSEPREPLADYRAEAEAESSAPAERFERSEVAAAAHQDRQEQV
FIEGAVRTAVTVEPRGNFLSVFIPPVKTLDDYLELIAQVEKVAEVTRIPVRIEGYAPPSD
PRVNVLKVTPDPGVVEVNIQPATSWAETVAITQGVYEDAREVKMTADKFMVDGRSVGTGG
GNHLVLGGASVNDSPFIRRPDLLKSFVLYWQRHPSLSYLFSGLFIGPTSQAPRIDEARHD
SLYELEIALAQVPNPVRDGEDKLPPPWLVDRLFRNLLVDVTGNTHRTEICIDKLFSPDGP
TGRLGLVEFRGFEMPPDPQMSLAQQLLLRALTAWFWREPQQGNLVRWGTALHDRFFLGHF
VWADFLEVLNDLRQAGYDFDPNWFEAQRQFRFPVHGSVEAGGVGLEISHALEPWNVLGET
GAIGGTVRYVDSSTERLQVRVSGLVAGRHIVSCNGRRVPMTPTGVPGEAVGGVRYKAWAP
ANCLHPNLPANAPLTFDIFDSWSGRSLGGCVYHVAHPGGRNYDDVPINSYEAEARRKARF
QDHGHTPGPVDMPPAEPPSEFPMTLDLRFRHPEY