Protein Info for PS417_04775 in Pseudomonas simiae WCS417

Annotation: short-chain dehydrogenase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 270 signal peptide" amino acids 1 to 19 (19 residues), see Phobius details PF00106: adh_short" amino acids 3 to 183 (181 residues), 156.4 bits, see alignment E=1.6e-49 PF08659: KR" amino acids 4 to 154 (151 residues), 30.4 bits, see alignment E=8.8e-11 PF01370: Epimerase" amino acids 4 to 83 (80 residues), 34.6 bits, see alignment E=3.5e-12 PF13561: adh_short_C2" amino acids 10 to 191 (182 residues), 117.2 bits, see alignment E=2.3e-37 PF08643: DUF1776" amino acids 72 to 257 (186 residues), 28.7 bits, see alignment E=2.3e-10

Best Hits

KEGG orthology group: None (inferred from 96% identity to pfs:PFLU0975)

Predicted SEED Role

"Oxidoreductase, short chain dehydrogenase/reductase family" in subsystem Ribitol, Xylitol, Arabitol, Mannitol and Sorbitol utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7U7B1 at UniProt or InterPro

Protein Sequence (270 amino acids)

>PS417_04775 short-chain dehydrogenase (Pseudomonas simiae WCS417)
MPNVLITGCSSGIGRALADAFKATGYRVWASARRAEDVAGLSAAGFNAVQLDVNDSAALQ
RLAEQLGELDVLVNNAGYGAMGPLLDGGTEAMQRQFETNVFSIVGVTQALFPALRRSKGV
VVNIGSVSGVLVTPFAGAYCASKAAVHALSDALRMELAPFGVRVMEVQPGAINTSFAKNA
GAQAELLINEQSPWWPLRDGIRARSQASQDKPTPANVFAADVLKAVQQPQPPRLLRSGNG
SRALPLMAALLPKGLLEKVLKKRFGLAGSL