Protein Info for GFF935 in Xanthobacter sp. DMC5

Annotation: Multidrug resistance protein 3

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 499 transmembrane" amino acids 27 to 49 (23 residues), see Phobius details amino acids 61 to 80 (20 residues), see Phobius details amino acids 92 to 118 (27 residues), see Phobius details amino acids 124 to 142 (19 residues), see Phobius details amino acids 154 to 172 (19 residues), see Phobius details amino acids 178 to 195 (18 residues), see Phobius details amino acids 215 to 234 (20 residues), see Phobius details amino acids 241 to 261 (21 residues), see Phobius details amino acids 283 to 306 (24 residues), see Phobius details amino acids 318 to 336 (19 residues), see Phobius details amino acids 348 to 367 (20 residues), see Phobius details amino acids 373 to 396 (24 residues), see Phobius details amino acids 418 to 438 (21 residues), see Phobius details amino acids 458 to 480 (23 residues), see Phobius details PF07690: MFS_1" amino acids 31 to 204 (174 residues), 131.3 bits, see alignment E=8.4e-42 amino acids 211 to 423 (213 residues), 64.5 bits, see alignment E=1.7e-21 PF06609: TRI12" amino acids 45 to 287 (243 residues), 33.6 bits, see alignment E=3.2e-12 PF00083: Sugar_tr" amino acids 61 to 194 (134 residues), 35.8 bits, see alignment E=9.1e-13

Best Hits

KEGG orthology group: None (inferred from 59% identity to azc:AZC_1860)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (499 amino acids)

>GFF935 Multidrug resistance protein 3 (Xanthobacter sp. DMC5)
MHQIDPQSPHASSGAKTTPSHAEIRRIIFGLMLAMLLGALDQTIVATALPTIGDAFGDFA
NLSWVVTAYLLAATVATPLYGKLSDIHGRRVMLLTAVAVFSAASVACALAPNLLALIIAR
AVQGLGGGGLISLSQTIIADLVSPRERGRYQAQIAGVFAASSIAGPVLGGLFAQYLNWTL
IFWVNLPIGLAALLITERRLRDLPRHERRHAMDYLGAALMAVASLMLLLALGWGGVRLPW
GSPLILALFAGTAVFVVLFIWRMRRAEEPFLPLGLLADKVVGRGMIASFLAFGGMVGLSI
FVPLYFETARGLSATQSGLGLIPVMGGVVIGAMLSGRAMARLVHYKRPAIAGLALSAGGL
LAIALAPAMPLVLVLALFAVIGVGMGTALPVCTVSIQNAVQPHLMGTTTGVMTFFRQLGG
ALAVAVLGAVLLAALAGVGAGDIESLARSADPARLSGAFSRVFATVSVLAALAAVALVFL
PERPLRSSVHASEGEGSIV