Protein Info for GFF901 in Xanthobacter sp. DMC5

Annotation: Urease subunit alpha

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 206 PF00547: Urease_gamma" amino acids 3 to 99 (97 residues), 153.9 bits, see alignment E=1.3e-49 TIGR00193: urease, gamma subunit" amino acids 3 to 100 (98 residues), 157.6 bits, see alignment E=8.5e-51 TIGR00192: urease, beta subunit" amino acids 107 to 205 (99 residues), 144.3 bits, see alignment E=1.2e-46 PF00699: Urease_beta" amino acids 108 to 204 (97 residues), 148.7 bits, see alignment E=4.2e-48

Best Hits

Swiss-Prot: 63% identical to URE23_DEIRA: Urease subunit gamma/beta (ureAB) from Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)

KEGG orthology group: K14048, urease subunit gamma/beta [EC: 3.5.1.5] (inferred from 88% identity to xau:Xaut_4155)

MetaCyc: 56% identical to urease subunit alpha UreA (Helicobacter pylori 26695)

Predicted SEED Role

"Urease beta subunit (EC 3.5.1.5)" in subsystem Urea decomposition (EC 3.5.1.5)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.5.1.5

Use Curated BLAST to search for 3.5.1.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (206 amino acids)

>GFF901 Urease subunit alpha (Xanthobacter sp. DMC5)
VLLTPREKDKLLVAMAAEVARKRLARGVKLNHPEAVALITDFVVEGARDGRTVAELMEAG
AKVLTSDQVMEGIAEMIHDIQVEATFPDGTKLVTVHHPIRGTPSETVPGELLPQEGDIHF
NEGAERVHLTVANTGDRPIQVGSHYHFFETNPALDFDRDKARGMRLDIAPGTAVRFEPGA
TRDVTLVPFGGKREVYGFRAAVAGKL