Protein Info for GFF900 in Xanthobacter sp. DMC5

Annotation: Urease subunit alpha 1

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00449: Urease_alpha
  • amino acids 5 to 122 (118 residues), 189.4 bits, E=3.6e-60
• TIGR01792: urease, alpha subunit
  • amino acids 6 to 570 (565 residues), 973 bits, E=2.7e-297
• PF01979: Amidohydro_1
  • amino acids 128 to 453 (326 residues), 265.5 bits, E=1.2e-82

Best Hits

Swiss-Prot: 82% identical to URE1_RHIME: Urease subunit alpha (ureC) from Rhizobium meliloti (strain 1021)

KEGG orthology group: K01428, urease subunit alpha [EC: 3.5.1.5] (inferred from 95% identity to xau:Xaut_4156)

MetaCyc: 82% identical to urease alpha subunit (Sinorhizobium meliloti Rm2011)
Urease. [EC: 3.5.1.5]

Predicted SEED Role

"Urease alpha subunit (EC 3.5.1.5)" in subsystem Urea decomposition (EC 3.5.1.5)

MetaCyc Pathways

• urea degradation II (1/1 steps found)
• superpathway of allantoin degradation in plants (4/8 steps found)

KEGG Metabolic Maps

• Arginine and proline metabolism
• Atrazine degradation
• Purine metabolism
• Urea cycle and metabolism of amino groups

Isozymes

Compare fitness of predicted isozymes for: 3.5.1.5

Use Curated BLAST to search for 3.5.1.5

Protein Sequence (570 amino acids)

>GFF900 Urease subunit alpha 1 (Xanthobacter sp. DMC5)
MSSSRMPRAAYAHMFGPTTGDRVRLADTSLVIEIEKDFTVYGEEVKFGGGKVIRDGMGQS
QVTNADGAMDTVITNAVILDHWGVVKADVGLKNGRIARIGKAGNPDVQAGVDIIIGPGTE
IIAGEGKILTAGGFDSHIHFICPQQIEEALASGVTTMLGGGTGPATGTFATTCTPGPWHI
ARMIEAADAFPMNLAFAGKGNASLPGALEEMVLAGACALKLHEDWGTTPSAIDCCLSVAD
ALDVQVMIHTDTLNESGFVEDTIAAFKGRTIHAFHTEGAGGGHAPDIIKVAGLPNVLPSS
TNPTRPFTRNTIDEHLDMLMVCHHLDPDIAEDLAFAESRIRKETIAAEDILHDIGALSMM
SSDSQAMGRVGEVIIRTWQTADKMKRQRGSLPGETDSDNIRARRYIAKYTINPAIAHGMS
RHIGSVEAGKLADLVLWTPAFFGVKPDLVIKGGAIAMAQMGDPNASIPTPQPVHYRPMFG
AFGRARTHTSLTFVSKVAIEDGLAGRLGIAKELVAVENTRSGISKKSMINNDATPHIEVD
PETYDVRADGELLVCEPADVLPMAQRYFLF